1403333-73-2

Upstream product

• 1403333-56-1 ethyl 1-tert-butyl-5-[2-(methylsulfanyl)pyrimidin-4-yl]-1H-pyrazole-3-carboxylate 
• 1403333-53-8 ethyl 4-[2-(methylsulfanyl)pyrimidin-4-yl]-2,4-dioxobutanoate 
• 496863-48-0 1-(2-methylsulfanyl-pyrimidin-4-yl)-ethanone 
• 1403333-68-5 ethyl 1-tert-butyl-5-[2-(methylsulfonyl)pyrimidin-4-yl]-1H-pyrazole-3-carboxylate 
• 108-95-2 phenol 

Downstream Products

• 1403332-60-4 N-benzyl-1-tert-butyl-5-(2-phenoxypyrimidin-4-yl)-1H-pyrazole-3-carboxamide 

Relevant academic research and scientific papers

PYRAZOLYL-PYRIMIDINE DERIVATIVES AS KINASE INHIBITORS

The present invention relates to pyrazolyl-pyrimidine derivatives which modulate the activity of protein kinases and are therefore useful in treating diseases caused by dysregulated protein kinase activity. The present invention also provides methods for preparing these compounds, pharmaceutical compositions comprising these compounds, and methods of treating diseases utilizing such compounds or the pharmaceutical compositions containing them.

PYRAZOLYL-PYRIMIDINE DERIVATIVES AS KINASE INHIBITORS

The present invention relates to pyrazolyl-pyrimidine derivatives which modulate the activity of protein kinases and are therefore useful in treating diseases caused by dysregulated protein kinase activity. The present invention also provides methods for preparing these compounds, pharmaceutical compositions comprising these compounds, and methods of treating diseases utilizing such compounds or the pharmaceutical compositions containing them.