1403558-96-2

Upstream product

• 1403558-99-5 (1′′RS)-2-methoxy-5-(2,3,4-trimethoxy-6-(1-(prop-2-ynyloxy)ethyl)phenyl)-furane 
• 1403558-98-4 (1RS)-1-(3,4,5-trimethoxy-2-(5-methoxyfurane-2-yl)phenyl)ethanol 
• 1403558-97-3 1-(3,4,5-trimethoxy-2-(5-methoxyfurane-2-yl)phenyl)ethanone 
• 1136-86-3 methyl (3,4,5-trimethoxyphenyl) ketone 

Downstream Products

• 1403559-00-1 (1′′RS)-6-(2,3,4-trimethoxy-6-(1-(prop-2-inyloxy)ethyl)phenyl)-2H-pyran-3(4H)-one 
• 1403558-95-1 (1′′RS)-5-diazo-1-(2,3,4-trimethoxy-6-(1-(prop-2-ynyloxy)ethyl)phenyl)pentan-1,4-dione 

Relevant academic research and scientific papers

Synthesis of oxa-B-ring analogs of colchicine through Rh-catalyzed intramolecular [5+2] cycloaddition

A synthetic approach towards (5R)-5-methyl-6-oxa-desacetamido colchicine as a conformationally defined non-natural colchicine analog with a modified B-ring was undertaken. The synthetic strategy was based on a Rh-catalyzed cascade reaction involving a [5+