1403558-97-3Relevant academic research and scientific papers
Synthesis of oxa-B-ring analogs of colchicine through Rh-catalyzed intramolecular [5+2] cycloaddition
Termath, Andreas Ole,Ritter, Stefanie,Kranz, Darius Paul,Neudoerfl, Joerg-Martin,Schmalz, Hans-Guenther,Koenig, Marcel,Prokop, Aram
, p. 4501 - 4507,7 (2012)
A synthetic approach towards (5R)-5-methyl-6-oxa-desacetamido colchicine as a conformationally defined non-natural colchicine analog with a modified B-ring was undertaken. The synthetic strategy was based on a Rh-catalyzed cascade reaction involving a [5+
