1403677-99-5

Usage

Uses

Used in Organic Synthesis:
Benzene, 1-(azidoMethyl)-4-(1,2,2-triphenylethenyl)is used as a key intermediate in organic synthesis for the development of new compounds and materials. Its azidomethyl and triphenylethenyl groups contribute to its unique reactivity, enabling the formation of a wide range of chemical products.
Used in Chemical Research:
This benzene derivative is utilized in chemical research to explore its properties and potential applications. Its unique structure and reactivity make it an interesting subject for studying various chemical reactions and mechanisms.
Used in Pharmaceutical Industry:
Benzene, 1-(azidoMethyl)-4-(1,2,2-triphenylethenyl)is employed as a building block in the synthesis of pharmaceutical compounds. Its versatile properties allow for the development of new drug candidates with potential therapeutic applications.
Used in Materials Science:
In the field of materials science, this benzene derivative is used for the development of advanced materials with specific properties. Its unique structure and reactivity enable the creation of materials with tailored characteristics for various applications, such as sensors, catalysts, or functional coatings.

Upstream product

• 125847-08-7 1-(4-methylphenyl)-1,2,2-triphenylethanol 
• 70592-06-2 1,1,2-triphenyl-2-(p-methylphenyl)ethylene 
• 1361969-01-8 (2-(4-(bromomethyl)phenyl)ethene-1,1,2-triyl)tribenzene 
• 101-81-5 Diphenylmethane 
• 134-84-9 4-Methylbenzophenone 
• 119-61-9 benzophenone 

Downstream Products

• 1403678-01-2 C₅₉H₇₀N₁₀O₁₃ 
• 1434839-89-0 1-[4-(isothiocyanatomethyl)phenyl]-1,2,2-triphenylethene 
• 1504585-16-3 1-[(4-aminomethyl)phenyl]-1,2,2-triphenylethene 
• 1504585-20-9 C₅₃H₅₇N₇O₁₇S₂ 

Relevant academic research and scientific papers

A tetraphenylethene and maltoheptaose conjugate with aggregation-induced emission (AIE) characteristic for temperature sensors

An amphiphilic maltoheptaose-tetraphenylethylene (Mal-TPE) conjugate can assemble in an aqueous medium and the aggregates exhibit an aggregation-induced emission (AIE) effect. The sizes of Mal-TPE aggregates decrease with the increase in temperature, resulting in temperature-dependent fluorescence properties.

Intermolecular hydrogen-bond interaction to promote thermoreversible 2'-deoxyuridine-based AIE-organogels

Fluorescent supramolecular nucleoside-based organogels or hydrogels have attracted increasing attention owing to their tunable stability, drug delivery, tissue engineering, and inherent biocompatibility for applications in designing sensors. As the temper

Aggregation-induced emission or aggregation-caused quenching? Impact of covalent bridge between tetraphenylethene and naphthalimide

Understanding the physical mechanisms governing aggregation-induced-emission (AIE) and aggregation-caused-quenching plays a vital role in developing functional AIE materials. In this work, tetraphenylethene (TPE, a classical AIEgen) and naphthalimide (NI, a popular fluorophore with ACQ characteristics) were connected through non-conjugated linkages and conjugated linkages. We showed that the nonconjugated-linkage of TPE to NI fragments leads to substantial PET in molecular aggregates and ACQ. In contrast, the conjugated connection between TPE and NI moieties results in the AIE phenomenon by suppressing twisted intramolecular charge transfer. This work provides an important guideline for the rational design of AIE materials.

TPE-2'-deoxynucleoside, fluorescent gel, and preparation methods and application of TPE-2'-deoxynucleoside and fluorescent gel

The invention discloses TPE-2'-deoxynucleoside, fluorescent gel, and preparation methods and application of the TPE-2'-deoxynucleoside and the fluorescent gel. The preparation method of TPE-2'-deoxynucleoside comprises the following steps: mixing alkyne-m

Self-assembly of tetraphenylethylene-based dendron into blue fluorescent nanoparticles with aggregation induced enhanced emission §

Abstract: Luminescent organic nanoassemblies have received great attention in recent years due to their potential applications in material science and bioimaging. Since most of the fluorophores undergo aggregation-caused quenching in the solid state, thei

Enzyme-responsive reporter molecules for selective localization and fluorescence imaging of pathogenic biofilms

Pathogenic bacteria and their biofilm formation are responsible for a broad spectrum of microbial infections. A novel enzyme-responsive reporter molecule (ERM-1), which can specifically recognize AmpC β-lactamase (Bla) in drug resistant bacteria, has been developed to enable the selective localization of biofilms.

Long-term fluorescent cellular tracing by the aggregates of AIE bioconjugates

There is a great demand for long-term cellular tracers because of their great importance in monitoring biological processes, pathological pathways, therapeutic effects, etc. Herein we report a new type of fluorescence "turn-on" probe for tracing live cell

Real-time monitoring of cell apoptosis and drug screening using fluorescent light-up probe with aggregation-induced emission characteristics

Real-time monitoring of cell apoptosis could provide valuable insights into early detection of therapy efficiency and evaluation of disease progression. In this work, we designed and synthesized a new live-cell-permeable, fluorescent light-up probe for real-time cell apoptosis imaging. The probe is comprised of a hydrophilic caspase-specific Asp-Glu-Val-Asp (DEVD) peptide and a hydrophobic tetraphenylethene (TPE) unit, a typical fluorogen with aggregation-induced emission characteristics. In aqueous solution, the probe is almost nonfluorescent but displays significant fluorescence enhancement in response to caspase-3/-7, which are activated in the apoptotic process and able to cleave the DEVD moieties. This fluorescence "turn-on" response is ascribed to aggregation of cleaved hydrophobic TPE residues, which restricts the intramolecular rotations of TPE phenyl rings and populates the radiative decay channels. The light-up nature of the probe allows real-time monitoring of caspase-3/-7 activities both in solutions and in living cells with a high signal-to-noise ratio. The probe provides a new opportunity to screen enzyme inhibitors and evaluate the apoptosis-associated drug efficacy.