1403767-29-2 Usage
Uses
Used in Organic Synthesis:
1,1-bis(propan-2-yl) 3-fluorocyclobutane-1,1-dicarboxylate is used as a reagent in organic synthesis for the preparation of various chemical compounds. Its unique structure allows for a wide range of reactions and transformations, making it a valuable building block in the synthesis of complex organic molecules.
Used in Pharmaceutical Research:
In the pharmaceutical industry, 1,1-bis(propan-2-yl) 3-fluorocyclobutane-1,1-dicarboxylate is used as a reagent in the development of new drugs. Its chemical properties enable it to be incorporated into drug candidates, potentially leading to the discovery of novel therapeutic agents with improved efficacy and safety profiles.
Used in Specialty Chemicals Production:
1,1-bis(propan-2-yl) 3-fluorocyclobutane-1,1-dicarboxylate is also used in the production of specialty chemicals, such as fragrances, dyes, and other high-value compounds. Its versatility and unique properties make it a valuable component in the synthesis of these specialty products.
Check Digit Verification of cas no
The CAS Registry Mumber 1403767-29-2 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,4,0,3,7,6 and 7 respectively; the second part has 2 digits, 2 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 1403767-29:
(9*1)+(8*4)+(7*0)+(6*3)+(5*7)+(4*6)+(3*7)+(2*2)+(1*9)=152
152 % 10 = 2
So 1403767-29-2 is a valid CAS Registry Number.
1403767-29-2Relevant academic research and scientific papers
Malashchuk, Andrii,Chernykh, Anton V.,Dobrydnev, Alexey V.,Grygorenko, Oleksandr O.
, p. 4897 - 4910 (2021)
A reliable methodology for constructing 6-fluoro-spiro[3.3]heptane scaffold is developed. A vast library of 2-mono- and 2,2-difunctionalized 6-fluoro-spiro[3.3]heptane-derived building blocks were obtained in a multigram scale (up to 302 g) though the convergent synthetic strategy. This class of compounds was designed for medicinal chemistry as fluorine-labelled conformationally restricted isosteres of cyclohexane framework. The structure was confirmed by X-ray diffraction study, and the physico-chemical properties (acidity, lipophilicity and water solubility) were characterized. Finally, the generation of virtual compound libraries using the LLAMA software showed that the monofluorinated spiro[3.3]heptane-derived building blocks demonstrated the highest propensity to populate the lead-like chemical space as compared to non- and difluorinated counterparts, as well as cyclohexane derivatives, while retaining similar three-dimensionality features.
