14039-10-2 Usage
General Description
1-(1-Adamantyl)-3-(2-chloroethyl)-3-nitrosourea, also known as ACNU, is a nitrosourea derivative that has been extensively studied for its potential use in cancer treatment. It is an alkylating agent that forms highly reactive alkyl groups, which can bind to DNA, leading to DNA damage and ultimately cell death. ACNU has shown promise in the treatment of various types of cancer, including brain tumors, due to its ability to cross the blood-brain barrier and exert its cytotoxic effects on tumor cells in the central nervous system. However, its clinical use is limited by its potential toxic effects on normal tissues, particularly bone marrow, and further research is needed to optimize its therapeutic potential.
Check Digit Verification of cas no
The CAS Registry Mumber 14039-10-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,4,0,3 and 9 respectively; the second part has 2 digits, 1 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 14039-10:
(7*1)+(6*4)+(5*0)+(4*3)+(3*9)+(2*1)+(1*0)=72
72 % 10 = 2
So 14039-10-2 is a valid CAS Registry Number.
InChI:InChI=1/C13H20ClN3O2/c14-1-2-17(16-19)12(18)15-13-6-9-3-10(7-13)5-11(4-9)8-13/h9-11H,1-8H2,(H,15,18)