1404-59-7 Usage
Uses
Used in Pharmaceutical Industry:
Rutamycin is used as an inhibitor of mitochondrial F1F0-ATPase for its cytotoxic effects on certain cancer cells, such as SW620 colon cancer cells, with an IC50 value of 36 μM. It also inhibits K-Ras plasma membrane localization in MDCK cells with an IC50 value of 3.49 nM.
Used in Research Applications:
Rutamycin is used as a bioprobe to study the organization of ATPase on the mitochondrial membrane, which is crucial for understanding the mechanisms of oxidative phosphorylation and electron transport.
Used in Antifungal Applications:
Rutamycin exhibits antifungal properties, making it useful in the treatment and prevention of fungal infections.
Used in Anthelmintic Applications:
Due to its nematocidal activities, Rutamycin can be employed in the treatment of nematode infections.
Check Digit Verification of cas no
The CAS Registry Mumber 1404-59-7 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,4,0 and 4 respectively; the second part has 2 digits, 5 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 1404-59:
(6*1)+(5*4)+(4*0)+(3*4)+(2*5)+(1*9)=57
57 % 10 = 7
So 1404-59-7 is a valid CAS Registry Number.
InChI:InChI=1/C44H72O11/c1-11-33-16-14-12-13-15-27(4)41(50)43(10,52)42(51)32(9)40(49)31(8)39(48)30(7)38(47)26(3)17-20-37(46)53-36-24-44(54-34(19-18-33)29(36)6)22-21-25(2)35(55-44)23-28(5)45/h12-14,16-17,20,25-36,38,40-41,45,47,49-50,52H,11,15,18-19,21-24H2,1-10H3/b13-12-,16-14+,20-17+/t25-,26-,27+,28+,29+,30-,31-,32-,33-,34-,35-,36-,38+,40+,41-,43+,44-/m1/s1
