140402-02-4

Upstream product

• 13224-05-0 2-(trimethylsilyl)-1,1-bis(phenylthio)ethane 
• 98-53-3 4-tercbutyl-cyclohexanone 
• 56881-81-3 4-tert-butyl-1-dibromomethylenecyclohexane 
• 13170-43-9 (trimethylsilyl)methylmagnesium chloride 
• 41924-26-9 bis((trimethylsilyl)methyl)zinc 
• 140461-77-4 1-tert-butyl-4-(bromomethylene)cyclohexane 

Relevant academic research and scientific papers

Preparation of allylsilanes by the olefination of carbonyl compounds using β-silylthioacetals

Titanocene(II)-promoted olefination of various carbonyl compounds using 1,1-bis(phenylthio)-2-triorganosilylethanes gave allylsilanes in good yields. γ-Alkoxy and alkylthio group substituted allylsilanes were also obtained by using carboxylic esters and thiolesters, respectively.

Preparation of 2-trimethylsilylmethyl-1-alkene; cross-coupling and protodesilylation sequence from 1,1-dibromo-1-alkene

A new method for the preparation of exomethylene type allylsilane is described. Selective mono-protodesilylation of 1-trimethylsilyl-2-trimethylsilylmethyl-2-alkenes 2 with PPTS afforded 2-trimethylsilylmethyl-1-alkenes 4 in excellent yields. Since the resulting allylsilanes 4 possess an exomethylene unit, the reactions of 4 with carbonyl compounds in the presence of Lewis acids gave the corresponding product 7 having an exomethylene unit in excellent yields.

Double Metal-Catalyzed Cross-Coupling Reactions of Alkenyl Sulfoximines with Diorganozinc Reagents: Synthesis of Optically Active Axial Chiral Allylic Silanes

Nickel- and magnesium-catalyzed cross-coupling reaction of the alkenyl sulfoximine 5 with the pure diorganozinc reagents 6a and 6b gave the optically active allylic silanes 7a and 7b, respectively.Single metal catalysis was sufficient for the substitution