140420-99-1

Basic information

• Product Name: 3-<(1R,6R)-6-(p-tolylsulfonyl)bicyclo<4.1.0>hept-1-yl>propanol
• Synonyms: 3-<(1R,6R)-6-(p-tolylsulfonyl)bicyclo<4.1.0>hept-1-yl>propanol
• CAS NO: 140420-99-1
• Molecular Weight: 308.442
• Mol File: 140420-99-1.mol

Chemical Properties

• CAS DataBase Reference: 3-<(1R,6R)-6-(p-tolylsulfonyl)bicyclo<4.1.0>hept-1-yl>propanol(CAS DataBase Reference)
• NIST Chemistry Reference: 3-<(1R,6R)-6-(p-tolylsulfonyl)bicyclo<4.1.0>hept-1-yl>propanol(140420-99-1)
• EPA Substance Registry System: 3-<(1R,6R)-6-(p-tolylsulfonyl)bicyclo<4.1.0>hept-1-yl>propanol(140420-99-1)

Safety Data

• Hazardous Substances Data: 140420-99-1(Hazardous Substances Data)

Upstream product

• 140629-82-9 3-<(1S,6R)-6-((S)-p-tolylsulfinyl)bicyclo<4.1.0>hept-1-yl>prop-1-ene 
• 169560-24-1 3-<(1S,6R)-6-(p-tolylthio)bicyclo<4.1.0>hept-1-yl>prop-1-ene 
• 169560-25-2 3-<(1S,6R)-6-(p-tolylsulfonyl)bicyclo<4.1.0>hept-1-yl>prop-1-ene 

Downstream Products

• 169560-30-9 3-<(1R,6R)-6-(p-tolylsulfonyl)bicyclo<4.1.0>hept-1-yl>propionic acid 

Relevant articles and documents

Asymmetric cyclopropanation by reaction of a γ-chloromethylated chiral vinylic sulfoxide with allylmagnesium bromide

An optically active vinylic sulfoxide bearing a leaving group at the γ-position was stereoselectively transformed into a chiral cyclopropane by means of a Michael addition with an allylmagnesinm bromide. The Michael induced ring-closure reaction requires both allylmagnesium bromide as a nucleophile and chloride as a leaving group for high diastereoselectivity. The absolute stereochemistry of the cycloadduct was confirmed by X-ray analysis.