169560-25-2

Upstream product

• 169560-24-1 3-<(1S,6R)-6-(p-tolylthio)bicyclo<4.1.0>hept-1-yl>prop-1-ene 
• 140629-82-9 3-<(1S,6R)-6-((S)-p-tolylsulfinyl)bicyclo<4.1.0>hept-1-yl>prop-1-ene 

Downstream Products

• 169560-26-3 (E)-1-<(1R,6R)-6-(p-tolylsulfonyl)bicyclo<4.1.0>hept-1-yl>prop-1-ene 
• 140420-99-1 3-<(1R,6R)-6-(p-tolylsulfonyl)bicyclo<4.1.0>hept-1-yl>propanol 
• 169560-27-4 (1R,6R)-6-(p-tolylsulfonyl)bicyclo<4.1.0>heptanecarbaldehyde 
• 169560-28-5 (1R,6R)-6-(p-tolylsulfonyl)bicyclo<4.1.0>hept-1-ylmethanol 
• 169560-30-9 3-<(1R,6R)-6-(p-tolylsulfonyl)bicyclo<4.1.0>hept-1-yl>propionic acid 

Relevant academic research and scientific papers

Asymmetric cyclopropanation by reaction of a γ-chloromethylated chiral vinylic sulfoxide with allylmagnesium bromide

An optically active vinylic sulfoxide bearing a leaving group at the γ-position was stereoselectively transformed into a chiral cyclopropane by means of a Michael addition with an allylmagnesinm bromide. The Michael induced ring-closure reaction requires both allylmagnesium bromide as a nucleophile and chloride as a leaving group for high diastereoselectivity. The absolute stereochemistry of the cycloadduct was confirmed by X-ray analysis.