140427-97-0Relevant articles and documents
POLYFLUORINE-SUBSTITUTED ALKYNES AND ALKADIYNOIC ACIDS II. SYNTHESIS OF ω-HYDROPOLYFLUOROALKYNES AND ALKADIYNOIC ACIDS BASED ON THEM
Radchenko, O. A.,Proshakova, E. V.,Kotlinskaya, A. N.,Il'chenko, A. Ya.
, p. 1281 - 1290 (2007/10/02)
The reaction of propargylaluminum sesquibromide with 7-monohydroperfluoroheptanal and methyl 7-monohydroperfluoroheptanoate in THF results in the formation of 1,3,3,4,10-pentahydroperfluoro-1-decyn-4-ol and 4-propargyl-1,3,3,4,10-pentahydroperfluoro-1-decyn-4-ol. 3-(Trihydroperfluoroalkoxy)-1-propynes were obtained from the alcohol-telomers and propargyl chloride.The corresponding mercury compounds, triazoles, diacetylenic alcohols, and carboxylic and hydroxamic acids were synthesized from the two types of alkynes.The acids are inhibitors of 5- and 15-lipoxygenases.