140445-85-8Relevant academic research and scientific papers
Novel synthese of heterocycles with N-(1-haloalkyl)azinium halides. Part 5. Preparation of N-substituted 1,4-dihydropyridines
Vanden Eynde,Mayence,Maquestiau,Anders
, p. 3291 - 3304 (1992)
Thirty N-substituted Hantzsch 1,4-dihydropyridines were prepared under mild and neutral conditions from N-substituted enaminocarbonyl derivatives and aldehydes activated under the form of N-(1-chloroalkyl)pyridinium chlorides by means of thionyl chloride
Synthesis of thiazolidine-4-carboxylic acids and N-(1-sulfonatoalkyl)pyridinium betaines from N-(1-chloroalkyl)pyrydinium chlorides
Anders, Ernst,Duray, Sara,Fuchs, Renate,Maas, Gerhard,Mayence, Annie,Eynde, Jean Jacques Vanden
, p. 383 - 386 (2007/10/03)
N-(1-chloroalkyl)pyridinium chlorides (1) react with L-cysteine to yield thiazolidine A-carboxylic acids.When salts 1 are not isolated, N-(1-sulfonatoalkyl)pyridinium betaines can be obtained under particular conditions.
A new and convenient method for the preparation of 2-substituted quinazolines
Vanden Eynde,Godin,Mayence,Maquestiau,Anders
, p. 867 - 869 (2007/10/02)
Aldehydes, converted in situ into N-(1-chloroalkyl)pyridinium chlorides using thionyl chloride and pyridine, react with 2-aminobenzylamine, under mild conditions, to yield 1,2,3,4-tetrahydroquinazolines. The latter can be aromatized readily by treatment w
Novel syntheses of heterocycles with N-(1-haloalkyl)azinium halides. Part 2. Preparation of N-unsubstituted 1,4-dihydropyridines
Vanden Eynde,D'Orazio,Mayence,Maquestiau,Anders
, p. 1263 - 1268 (2007/10/02)
N-(1-Chloroalkyl)pyridinium chlorides, prepared from thionyl chloride, pyridine, and aldehydes, readily react with enaminocarbonyl derivatives to yield 1,4-dihydropyridines under mild and neutral conditions.
NOVEL SYNTHESES OF HETEROCYCLES WITH N-(1-HALOALKYL)AZINIUM HALIDES: PART 6. PREPARATION OF 2,3,4,5,10,11-HEXAHYDRO-1H-DIBENZODIAZEPIN-1-ONES
Eynde, J. -J. Vanden,Mayence, A.,Maquestiau, A.,Anders E.
, p. 801 - 806 (2007/10/02)
Conversion of aldehydes into N-(1-chloroalkyl)pyridinium chlorides (by means of pyridine and thionyl chloride) and further reaction with 3-(2-aminophenyl)amino-5,5-dimethyl-2-cyclohexenone provide a novel and efficient route to the title compounds.
