140472-53-3

Upstream product

• 17375-64-3 3-acetyl-2-phenylindole 
• 100-52-7 benzaldehyde 
• 4535-09-5 N-phenyl-fluorenoneimine-N-oxide 
• 37845-36-6 1,5-diphenyl-1-penten-4-yn-3-one 
• 25365-71-3 2-phenyl-1H-indol-3-carboxaldehyde 
• 948-65-2 2-phenyl-indole 
• 88981-42-4 Chloromethyl styryl ketone 
• 1527-91-9 N-phenylbenzamidine 
• 122-57-6 1-Phenylbut-1-en-3-one 

Downstream Products

• 1544390-03-5 C₂₉H₂₁N₃ 
• 140472-57-7 4-methyl-1-(1'-methyl-2'-phenylindol-3'-yl)-4-nitro-3-phenylpentan-1-one 
• 140472-60-2 5,5-dimethyl-2-(1'-methyl-2'-phenylindol-3'-yl)-4-phenyl-1-pyrroline 1-oxide 
• 140472-61-3 5,5-dimethyl-2-(1'-methyl-2'-phenylindol-3'-yl)-4-phenyl-1-pyrroline 
• 140472-54-4 1-(1'-methyl-2'-phenylindol-3'-yl)-3-phenylprop-2-en-1-one 

Relevant academic research and scientific papers

Direct Synthesis of 3-Acylindoles through Rhodium(III)-Catalyzed Annulation of N-Phenylamidines with α-Cl Ketones

In the present study, a novel synthetic strategy to directly produce versatile 3-acylindoles through Rh(III)-catalyzed C-H activation and annulation cascade of N-phenylamidines with α-Cl ketones was developed, in which α-Cl ketones serve as unusual one-carbon (sp3) synthons. This strategy features high regioselectivity, efficiency, wide substrate tolerance, and mild reaction conditions, which further underscore its synthetic utility in drug molecule synthesis.

A New Method for the Synthesis of 3-Substituted Indoles

Starting from readily accessible nitrones and electron-deficient acetylenes, a highly efficient and versatile synthetic protocol for 3-substituted indoles has been developed.

Synthesis of 1H-Indol-3-ylpyrazole derivatives from 1,3,5-triketones and arylhydrazines: One-pot construction of pyrazole and indole rings

The reaction of 1,3,5-triketones and arylhydrazines provided indolylpyrazole derivatives in a one-pot reaction in good to moderate yields. Both the pyrazole and indole rings were constructed simultaneously with phenylhydrazine, RCOCH2CO- moiety for the py

Nitrones and Oxaziridines. XLII Synthesis of Indol-3-yl Substituted 1-Pyrroline 1-Oxides

The 1-pyrroline 1-oxides (13), (14), (16) and (18) with indol-3-yl substituents attached to the 2- or 4-positions have been synthesized by reductive cyclization of the related γ-nitro ketones.The corresponding 1-pyrrolines (15), (17) and (19) have also be