140677-52-7Relevant academic research and scientific papers
Asymmetric Synthesis of Pyrrolodiazepine Derivatives as Potential Antihypertensive Drugs
Bolos, Jordi,Perez, Angel,Gubert, Santiago,Anglada, Luis,Sacristan, Aurelio,Ortiz, Jose A.
, p. 3535 - 3539 (2007/10/02)
The asymmetric synthesis of compound 1, with potential angiotensin-converting enzyme inhibitory activity, is reported.From the chiral precursor 5, readily available from L-glutamic acid, two strategies to the key heterocyclic system pyrrolodia
