14073-27-9Relevant articles and documents
In silico studies and β-cyclodextrin mediated neutral synthesis of 4-oxo-4,5,6,7-tetrahydroindoles of potential biological interest
Dhananjaya,Rao, A.V. Dhanunjaya,Hossain, Kazi Amirul,Anna, Venkateswara Rao,Pal, Manojit
supporting information, (2020/07/23)
Prompted by the in silico docking study predictions the first β-cyclodextrin (β-CD) mediated synthesis of 4-oxo-4,5,6,7-tetrahydroindoles in water was achieved via a 3-component reaction under neutral conditions. A range of compounds was prepared by using
REACTIONS OF AZIRINES WITH SULFUR NUCLEOPHILES. 4. TREATMENT OF 2H-AZIRINE WITH MERCAPTOSUBSTITUTED ACIDS. REACTIONS OF AZIRIDINYL ALKYL SULFIDES WITH CARBOXYLIC ACIDS AND ACYL CHLORIDE DERIVATIVES
El'kinson, R.S.,Eremeev, A.V.
, p. 161 - 166 (2007/10/02)
Treatment of 2H-azirines with mercaptosubstituted acids and their derivatives leads to β-ketoamides and 2-aziridinyl alkyl sulfides, respectively. 2-Aziridinyl alkyl sulfides, in turn, react with carboxylic acids to give β-ketoamides and substituted ethanethiol derivatives.Acylation of 2-aziridinyl alkyl sulfides with acyl halides generates a variety of products, depending on the reaction conditions; either products derived from cleavage and isomerization of the aziridinyl ring or (1-acylaziridinyl-2) alkyl sulfides are obtained.
Substituted 2-phenyl-4,6,7,8-tetrahydrofuro and 1,4,5,6,7,8-hexahydropyrrolo[3,2,-c]azepines
-
, (2008/06/13)
Substituted 2-phenyl-4,6,7,8-tetrahydrofuro- and 1,4,5,6,7,8-hexahydropyrrolo[3,2-c]azepines and physiologically tolerable acid addition salts thereof possessing analgesic and tranquilizing properties, and a process for their preparation are described.