1407496-18-7

Basic information

• Product Name: C₂₁H₁₅Cl₂F₄N₅O₂
• Synonyms: C₂₁H₁₅Cl₂F₄N₅O₂
• CAS NO: 1407496-18-7
• Molecular Weight: 516.282
• Mol File: 1407496-18-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₂₁H₁₅Cl₂F₄N₅O₂(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₁H₁₅Cl₂F₄N₅O₂(1407496-18-7)
• EPA Substance Registry System: C₂₁H₁₅Cl₂F₄N₅O₂(1407496-18-7)

Safety Data

• Hazardous Substances Data: 1407496-18-7(Hazardous Substances Data)

Upstream product

• 1407496-22-3 6-bromo-4-chloro-2-(trifluoromethyl)pyrido[2,3-d]pyrimidine 
• 330156-50-8 (R)-1-(2,6-dichloro-3-fluorophenyl)ethan-1-ol 
• 1040377-08-9 2-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl]ethanol 
• 1407496-23-4 C₁₆H₈BrCl₂F₄N₃O 

Relevant articles and documents

Multisubstituted quinoxalines and pyrido[2,3-d]pyrimidines: Synthesis and SAR study as tyrosine kinase c-Met inhibitors

Two series of new analogues were designed by replacing the quinoline scaffold of our earlier lead 2 (zgwatinib) with quinoxaline and pyrido[2,3-d]pyrimidine frameworks. Moderate c-Met inhibitory activity was observed in the quinoxaline series. Among the p