1407499-72-2

Upstream product

• 359700-09-7 (E)-3-(1-(tert-butoxycarbonyl)-1H-indol-3-yl)acrylic acid 
• 1407499-42-6 (E)-tert-butyl 3-(3-(2-(3-hydroxybenzoyl)-1-isopropylhydrazinyl)-3-oxoprop-1-enyl)-1H-indole-1-carboxylate 
• 106-93-4 ethylene dibromide 
• 15563-13-0 3-hydroxy-N'-isopropylbenzohydrazide 

Downstream Products

• 1407499-46-0 (E)-tert-butyl 3-(3-(1-isopropyl-2-(3-(2-morpholinoethoxy)benzoyl)hydrazinyl)-3-oxoprop-1-enyl)-1H-indole-1-carboxylate 

Relevant academic research and scientific papers

Novel Indole Derivative or Pharmaceutically Acceptable Salt Thereof, Preparation Method Thereof, and Pharmaceutical Composition for Preventing or Treating Metabolic Diseases Containing Same as Active Ingredient

The present invention relates to an indole derivative, The indole derivative according to the present invention effectively inhibits the activity of diacylglycerol acyltransferase (DGAT) which induces metabolic diseases, such as obesity, diabetes, hyperlipidemia, or fatty liver and the like in lipid metabolism, thereby effectively regulating lipid metabolism and energy metabolism, and thus can be useful in pharmaceutical compositions for preventing or treating metabolic disease.