14080-34-3 Usage
Uses
Used in Pharmaceutical Synthesis:
Pyrimidine, 2-methyl-5-nitro(8CI,9CI) is used as a key intermediate in the synthesis of various pharmaceuticals for its ability to contribute to the development of new drugs with potential therapeutic applications.
Used in Agrochemical Synthesis:
In the agrochemical industry, Pyrimidine, 2-methyl-5-nitro(8CI,9CI) serves as a crucial component in the creation of agrochemicals, aiding in the development of pesticides and other agricultural products to enhance crop protection and yield.
Used in Materials Science:
Pyrimidine, 2-methyl-5-nitro(8CI,9CI) is utilized in materials science for its potential to contribute to the development of new materials with unique properties, such as those used in electronic devices or other advanced applications.
It is important to handle Pyrimidine, 2-methyl-5-nitro(8CI,9CI) with care due to the potential hazards associated with nitro compounds, which can be explosive if mishandled. Proper safety measures should be taken during its synthesis and use to ensure the safety of personnel and the integrity of the process.
Check Digit Verification of cas no
The CAS Registry Mumber 14080-34-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,4,0,8 and 0 respectively; the second part has 2 digits, 3 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 14080-34:
(7*1)+(6*4)+(5*0)+(4*8)+(3*0)+(2*3)+(1*4)=73
73 % 10 = 3
So 14080-34-3 is a valid CAS Registry Number.
InChI:InChI=1/C5H5N3O2/c1-4-6-2-5(3-7-4)8(9)10/h2-3H,1H3
14080-34-3Relevant academic research and scientific papers
Ring Transformations in Reactions of Heterocyclic Compounds with Nucleophiles. Conversion of 5-Nitropyrimidine into 2-Substituted 5-Nitropyrimidine and 2-Amino-5-nitropyridines by Amidines
Barczynski, P.,Plas, H. C. van der
, p. 1077 - 1080 (2007/10/02)
The reaction of 5-nitropyrimidine (1) with benzamidine, pivalamidine, acetamidine, propionamidine, α-phenylacetamidine, O-methylisourea hydrochlorides, and cyanamide in ethanolic solution in the presence of triethylamine has been investigated.It was found that reaction of 1 with alkyl(aryl) amidines, having no active methylene groups attached to the amidine moiety (pivalamidine, benzamidine), exclusively formed the corresponding 2-substituted 5-nitropyrimidines in good yields.With acetamidine and propionamidine, in addition to the formation of the 2-substituted 5-nitropyrimidines, the formation of 2-amino-5-nitropyridines also was observed; with α-phenylacetamidine a 2-amino-5-nitropyridine derivative exclusively was obtained.The reaction of 1 with both O-methylisourea and cyanamide leads to 2-amino-5-nitropyrimidine.These reactions provide new examples of degenerate ring transformations of the pyrimidine ring system and of the ring transformation of pyrimidines into pyridines.
