14080-32-1 Usage
Description
Pyrimidine, 5-nitro(8CI,9CI) is a derivative of the basic aromatic organic compound, pyrimidine, which is structurally similar to benzene and pyridine. It contains two nitrogen atoms at non-adjacent positions and is one of the fundamental building blocks of nucleic acids such as DNA and RNA. This specific compound is characterized by the substitution of a nitro group at the 5th position, which is a functional group consisting of a nitrogen atom connected to a hydrogen or organic group and an oxygen atom bonded to another oxygen atom with a negative charge. This nitro group is typically attached to a carbon or sulfur atom in the organic molecule.
Uses
Used in Pharmaceutical Industry:
Pyrimidine, 5-nitro(8CI,9CI) is used as an intermediate compound for the synthesis of various pharmaceuticals. Its unique structure and the presence of the nitro group make it a valuable building block in the development of new drugs, particularly those targeting DNA and RNA-related processes.
Used in Chemical Research:
In the field of chemical research, Pyrimidine, 5-nitro(8CI,9CI) serves as a key compound for studying the properties and reactions of nitro-containing organic molecules. Its reactivity and the potential for further functionalization make it an important subject of investigation in organic chemistry.
Used in Material Science:
Pyrimidine, 5-nitro(8CI,9CI) can be utilized in the development of novel materials with specific properties, such as those with enhanced stability or reactivity. Its incorporation into polymers or other complex structures may lead to materials with unique characteristics, making it a valuable component in material science research.
Check Digit Verification of cas no
The CAS Registry Mumber 14080-32-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,4,0,8 and 0 respectively; the second part has 2 digits, 3 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 14080-32:
(7*1)+(6*4)+(5*0)+(4*8)+(3*0)+(2*3)+(1*2)=71
71 % 10 = 1
So 14080-32-1 is a valid CAS Registry Number.
InChI:InChI=1/C4H3N3O2/c8-7(9)4-1-5-3-6-2-4/h1-3H
14080-32-1Relevant articles and documents
Electron-deficient heteroarenium salts: An organocatalytic tool for activation of hydrogen peroxide in oxidations
?turala, Ji?í,Bohá?ová, Soňa,Chudoba, Josef,Metelková, Radka,Cibulka, Radek
, p. 2676 - 2699 (2015/03/18)
A series of monosubstituted pyrimidinium and pyrazinium triflates and 3,5-disubstituted pyridinium triflates were prepared and tested as simple catalysts of oxidations with hydrogen peroxide, using sulfoxidation as a model reaction. Their catalytic efficiency strongly depends on the type of substituent and is remarkable for derivatives with an electron-withdrawing group, showing reactivity comparable to that of flavinium salts which are the prominent organocatalysts for oxygenations. Because of their high stability and good accessibility, 4-(trifluoromethyl)pyrimidinium and 3,5-dinitropyridinium triflates are the catalysts of choice and were shown to catalyze oxidation of aliphatic and aromatic sulfides to sulfoxides, giving quantitative conversions, high preparative yields and excellent chemoselectivity. The high efficiency of electron-poor heteroarenium salts is rationalized by their ability to readily form adducts with nucleophiles, as documented by low pKR+ values (pKR+ red > -0.5 V). Hydrogen peroxide adducts formed in situ during catalytic oxidation act as substrate oxidizing agents. The Gibbs free energies of oxygen transfer from these heterocyclic hydroperoxides to thioanisole, obtained by calculations at the B3LYP/6-311++g(d,p) level, showed that they are much stronger oxidizing agents than alkyl hydroperoxides and in some cases are almost comparable to derivatives of flavin hydroperoxide acting as oxidizing agents in monooxygenases.
