1408233-55-5

Basic information

• Product Name: C₁₅H₁₂ClNO₅S
• Synonyms: C₁₅H₁₂ClNO₅S
• CAS NO: 1408233-55-5
• Molecular Weight: 353.783
• Mol File: 1408233-55-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₁₅H₁₂ClNO₅S(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₅H₁₂ClNO₅S(1408233-55-5)
• EPA Substance Registry System: C₁₅H₁₂ClNO₅S(1408233-55-5)

Safety Data

• Hazardous Substances Data: 1408233-55-5(Hazardous Substances Data)

Upstream product

• 15206-55-0 methyl 2-oxo-2-phenylacetate 
• 38114-34-0 2-hydroxyimino-2-phenylacetic acid methyl ester 
• 98-60-2 4-chlorobenzenesulfonyl chloride 

Relevant articles and documents

Double nucleophilic N-alkylation of α-oxime-esters with Grignard reagents

Double nucleophilic N-alkylation of α-oxime-esters, affording N,N-dialkyl-α-amino acids is herein described. Grignard reagents accomplished double N-alkylations via umpolung and various N,N-dialkylated α-amino acids were successfully synthesized in 15 min. Both electron-withdrawing sulfonyl groups and electron-donating silyl and methyl groups on oximes were available. Alkylmagnesium species and (E)-configuration of α-oxime-ester were essential to this cascade reaction.