1408348-55-9

Upstream product

• 35661-60-0 Fmoc-Leu-OH 
• 35737-10-1 N-Fmoc-β-alanine 
• 1408287-02-4 (2S,4S,6S)-2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-6-hydroxy-4-methyl-8-oxodecanoic acid 
• 1408286-92-9 (2S,4R)-2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-4-methyldecanoic acid 
• 1408287-01-3 (S)-(9H-fluoren-9-yl)methyl 1-[benzyl(2-hydroxyethyl)amino]propan-2-yl carbamate 
• 94744-50-0 N-[(9H-fluoren-9-ylmethoxy)carbonyl]-α-aminoisobutyric acid 

Relevant academic research and scientific papers

Synthesis of the peptaibol framework of the anticancer agent culicinin D: Stereochemical assignment of the AHMOD moiety

The postulated structure of the potent anticancer peptaibol culicinin D has been synthesized using Fmoc-based solid-phase peptide synthesis (SPPS). Comparison of the 1H NMR data for the reported structure of culicinin D with the data obtained for the two synthetic polypeptides epimeric at C-6 in the AHMOD unit established the C-6 stereochemistry of the AHMOD residue in the natural product to be (R).