1408463-85-3Relevant academic research and scientific papers
Synthesis, characterization, and in vitro microbial evaluation of some new 4H-chromene and quinoline derivatives of 1H-pyrazole
Thumar, Nilesh J.,Patel, Manish P.
, p. 1169 - 1178 (2013/01/15)
A new series of nine derivatives of 4H-pyrano[3,2-c]chromene and 12 derivatives of N-thiazolyl-4H-quinoline of 1H-pyrazole has been synthesized by one pot base catalyzed cyclocondensation reaction of 1H-pyrazole-4-carbaldehyde, malononitrile, and 4-hydroxy coumarin or β-enaminones, respectively. All the synthesized compounds were characterized by elemental analysis, FT-IR, 1H NMR, 13C NMR spectral data and were further screened, against a panel of pathogenic strains of bacteria and fungi.
