14088-41-6

Basic information

• Product Name: 3-Buten-2-one, 4-amino-4-phenyl-
• Synonyms: 1-Imino-1-phenyl-butanon-(3);4-Amino-4-phenyl-but-3-en-2-on;4-amino-4-phenyl-but-3-en-2-one;1-Amino-1-phenyl-buten-(2)-on-(3);Benzoylacetonamin;4-amino-4-phenylbut-3-en-2-one
• CAS NO: 14088-41-6
• Molecular Formula: C10H11NO
• Molecular Weight: 161.203
• Mol File: 14088-41-6.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 3-Buten-2-one, 4-amino-4-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Buten-2-one, 4-amino-4-phenyl-(14088-41-6)
• EPA Substance Registry System: 3-Buten-2-one, 4-amino-4-phenyl-(14088-41-6)

Safety Data

• Hazardous Substances Data: 14088-41-6(Hazardous Substances Data)

Upstream product

• 93-91-4 1-phenylbutan-1,3-dione 
• 1136-45-4 5-methyl-3-phenylisoxazol-4-carboxylic acid 
• 1008-74-8 5-methyl-3-phenylisoxazole 
• 55337-45-6 4-ethoxy-4-phenyl-but-3-en-2-one 
• 7664-41-7 ammonia 
• 114078-85-2 5-Bromo-4-methyl-6-phenyl-[1,2,3]triazine 
• 100-47-0 benzonitrile 
• 123-54-6 acetylacetone 

Downstream Products

• 85814-61-5 1-(2,5-diphenyl-1H-pyrrol-3-yl)ethanone 
• 885700-91-4 6-acetyl-2-(4-methoxyphenyl)-3,3,5-triphenyl-4H-1,2,4,3λ4-triazaborine 
• 1008-75-9 3-methyl-5-phenylisoxazole 
• 885700-88-9 5-((4-methoxyphenyl)diazenyl)-6-methyl-2,2,6-triphenyl-3H-1,3,2λ4-oxazaborine 

Relevant articles and documents

Tetrasubstituted 1,3-Enynes by Gold-Catalyzed Direct C(sp2)-H Alkynylation of Acceptor-Substituted Enamines

A gold-catalyzed synthesis of tetrasubstituted 1,3-enynes from hypervalent iodine(III) reagents and activated alkenes is reported. This reaction involves an in situ formed alkynyl Au(III) species and a subsequent direct C(sp2)-H functionalization of alkenes, offering 26 enynes in 62-92% yield with excellent functional group tolerance.

Asymmetric Aza-Diels-Alder Reactions of in Situ Generated β,β-Disubstituted α,β-Unsaturated N-H Ketimines Catalyzed by Chiral Phosphoric Acids

A novel asymmetric synthesis of dihydropyridinones with vicinal quaternary stereocenters has been realized by asymmetric aza-Diels-Alder reactions of 3-amido allylic alcohols with oxazolones enabled by chiral phosphoric acid catalysis. A series of aryl/alkyl- and alkyl/alkyl-disubstituted 3-amido allylic tertiary alcohols and 4-substituted oxazolones could be well tolerated in these reactions, producing dihydropyridinones with excellent diastereoselectivities and high enantioselectivities. Mechanistic study and control experiments were performed to shed light on the reaction mechanism, in which a configurationally defined β,β-disubstituted α,β-unsaturated N-H ketimine was proposed as the key intermediate.

The substitution of 5-halo-1,2,3-triazines with electrolytically generated superoxide

Electrolytically generated superoxide reacted with 5-halo-1,2,3-triazines 1 to afford 5-hydroxy-1,2,3-triazines 2. Reaction of 1 with hydroxide anion or potassium superoxide resulted in complicated mixture of products, therefore the reaction was specific for electrogenerated superoxide. The reaction mechanism was investigated with electrochemical methods, and it was revealed that one electron transfer from superoxide to 1 initialized the reaction.