14088-61-0

Upstream product

• 930-91-6 2-hydroxymethylenecyclopentanone 
• 1192-54-7 2-formylcyclopentanone 
• 120-92-3 cyclopentanone 

Downstream Products

• 22323-97-3 2-methoxycyclopent-2-en-1-one 
• 71996-27-5 2-(phenylselenenyl)-2-cyclopentenone 
• 99892-43-0 1-(1-Ethoxy-2-oxocyclopentyl)-4-phenyl-1,2,4-triazolidin-3,5-dion 
• 98883-35-3 10-benzyl-8,9-dihydropyrido[1,2-a]indol-6(7H)-one 
• 15128-52-6 1,2,3,9-tetrahydro-4H-carbazol-4-one 
• 87506-08-9 (E)-2-styrylcyclopent-2-enone 
• 34780-08-0 2-(phenylthio)cyclopent-2-en-1-one 
• 10481-34-2 2-bromo-2-cyclopenten-1-one 
• 14924-53-9 ethyl cyclobutylcarboxylate 
• 52190-40-6 2-(phenylthio)cyclopentanone 
• 108592-87-6 8-tert-Butyl-1,9-diaza-7-phosphabicyclo<4.3.0>nona-6,8-dien-2-on 

Relevant academic research and scientific papers

Practical Application of the Aqueous 'Sulfonyl-Azide-Free' (SAFE) Diazo Transfer Protocol to Less α-C-H Acidic Ketones and Esters

The earlier described 'sulfonyl-Azide-free' ('SAFE') protocol for diazo transfer to CH-Acidic 1,3-dicarbonyl compounds (and their similarly activated congeners) has been extended to the less reactive monocarbonyl substrates, which previously required a se

CYCLOADDITIONS OF DISUBSTITUTED DIAZO COMPOUNDS TO P-CHLORO(BISTRIMETHYLSILYL) METHYLENE PHOSPHINE.

Disubstituted diazo compounds rapidly add to P-chloro (bistrimethylsilyl) methylene phosphine at low temperature. 1H, 31P and 13C NMR allow the characterization of the resulting cycloadducts and the establisment of the stereochemistry of the resulting cycloadducts which are potential precursors of ?3λ5 bis methylene phosphorane by nitrogen extrusion.

A Simple Procedure for Preparation of α-Diazocarbonyl Compounds

The use of 1,8-diazabicycloundec-7-ene as a base in Regitz reaction leads to improved yields of α-diazocarbonyl compounds in much shorter time (15 min).

REGIOSPECIFIC SYNTHESIS OF α-(PHENYLTHIO)CYCLOALKENONES AND OF α-PHENYL-α-(PHENYLTHIO)KETONES VIA αα-ADDITION OF PHENYLSULPHENYL CHLORIDE TO α-DIAZOKETONES

Cyclic α-diazoketones react with phenylsulphenyl chloride at room temperature to furnish α-chloro-α-(phenylthio)cycloalkanones which undergo ready dehydrochlorination to α-(phenylthio)cycloalkenones when treated with triethylamine; acyclic, terminal α-diazoketones also furnish α-chloro-α-(phenylthio)adducts which are useful electrophiles in the synthesis of α-phenyl-α-(phenylthio)ketones.

Polymer Anchored Sulfonylazide for Deformylating Diazo Group Transfer and the Synthesis of Diazo-cyclopolyenes

Polymer anchored sulfonylazide is compared with its efficiency in the diazogroup transfer reaction of tosylazide.The resulting yields with the polymeric reaction are slihgtly lower than with tosylazide.However the greater thermostability of polymeric sulfonyl azide and its workup procedure make this alternative very attractive for synthesis.The reaction of polymeric sulfonyl azide with cyclic polyenes gives very small yields compared with the monomeric reaction.The attempt to generate diazocyclononatetraene by an alternative route leads only to the secondary product namely indene.At low temperature, and intermediate diazocompound is, however, observed, which is tentatively assigned to structure 12. - Key words: Polymer-bound Sulfonylazide, Azogroup Transfer, Synthesis of Diazo-cyclopolyenes