34780-08-0Relevant academic research and scientific papers
Iodine-catalyzed selective synthesis of 2-sulfanylphenols via oxidative aromatization of cyclohexanones and disulfides
Ge, Wenlei,Zhu, Xun,Wei, Yunyang
supporting information, p. 3014 - 3021 (2014/03/21)
Iodine-catalyzed intermolecular dehydrogenative aromatizations of six-membered cyclohexanones for the selective synthesis of 2-sulfanylphenols have been developed. Both aryl and alkyl disulfides can be used as sulfanylation reagents to give the desired pr
NaOH-Catalyzed Thiolysis of α,β-Epoxyketones in Water. A Key Step in the Synthesis of Target Molecules Starting from α,β -Unsaturated Ketones
Fringuelli, Francesco,Pizzo, Ferdinando,Vaccaro, Luigi
, p. 2315 - 2321 (2007/10/03)
NaOH (0.02-0.3 molar equiv) is an efficient catalyst for the thiolysis reactions of α,β-epoxy ketones with alkyl and aryl thiols in water. Thiolysis of 3,4-epoxyheptan-2-one (1) with thiols 2a-d has been accomplished in mild conditions (30 °C and pH 6 or
Preparation of α-sulfenyl enones by thermal fragmentation of β-sulfenyl enol triflates
Hynes Jr., John,Nasser, Talal,Overman, Larry E.,Watson, Donald A.
, p. 929 - 931 (2007/10/03)
(equation presented) The synthetic scope and mechanism of the fragmentation of cyclic β-sulfenyl enol triflates to give α-sulfenyl enones are described. This transformation is the central step in a mild, functional group-tolerant method for preparing α-su
Cyclopentannulations Leading to the Synthesis of Bicyclic Conjugated Enediones
Yechezekel, Tamar,Ghera, Eugene,Ostercamp, Daryl,Hassner, Alfred
, p. 5135 - 5142 (2007/10/02)
Base-induced reactions of 1-(phenylsulfonyl)-2-methylene-3-bromopropane (4) with 2-(phenylsulfonyl)-2-cycloalkenones 8a-d were investigated with the ultimate purpose to develop a route leading to bicyclic conjugated enediones.Low-temperature, fast-quenche
Regiochemical Control in the Alkylation of Tetrahydroindanones
Lee, Thomas V.,Toczek, Judy
, p. 759 - 762 (2007/10/02)
The first regiospecific alkylation of the 3a,4,7,7a-tetrahydroindanone (1) has been achieved, by use of a phenylthio group acting as a directing group for enolate anion generation or as a blocking group which permits the formation of the regioisomeric eno
ALKYNE-COBALT COMPLEXES AS PROSTAGLANDIN SYNTHONS. IV. A POSSIBLE APPROACH VIA 2-PHENYLTHIOCYCLOPENT-2-ENONE.
Daalman, Lachlan,Newton, Roger F.,Pauson, Peter L.,Wadsworth, Alan
, p. 3150 - 3164 (2007/10/02)
The effectiveness of (phenylthioethyne)hexacarbonyldicobalt as a precursor of mono, di- and tricyclic 2-phenylthiocyclopent-2-en-1-ones is demonstrated.These ketones are shown to undergo the expected 1,4-additions of mixed cuprate reagents, but further elaboration of the products to prostaglandin analogues was not pursued when models of the required alkylation reactions were found to proceed very poorly.
REGIOSPECIFIC SYNTHESIS OF α-(PHENYLTHIO)CYCLOALKENONES AND OF α-PHENYL-α-(PHENYLTHIO)KETONES VIA αα-ADDITION OF PHENYLSULPHENYL CHLORIDE TO α-DIAZOKETONES
McKervey, M. Anthony,Ratananukul, Piniti
, p. 117 - 120 (2007/10/02)
Cyclic α-diazoketones react with phenylsulphenyl chloride at room temperature to furnish α-chloro-α-(phenylthio)cycloalkanones which undergo ready dehydrochlorination to α-(phenylthio)cycloalkenones when treated with triethylamine; acyclic, terminal α-diazoketones also furnish α-chloro-α-(phenylthio)adducts which are useful electrophiles in the synthesis of α-phenyl-α-(phenylthio)ketones.
