140925-47-9

Upstream product

• 140925-57-1 (3R,4R,5S,6S)-7-Benzyloxy-2,4,6-trimethyl-hept-1-ene-3,5-diol 
• 152192-51-3 (4S,5R,6R)-4-((S)-2-Benzyloxy-1-methyl-ethyl)-2,2-di-tert-butyl-6-isopropenyl-5-methyl-[1,3,2]dioxasilinane 
• 140925-38-8 (2S,4S,5R)-1-benzyloxy-5-hydroxy-2,4,6-trimethylhept-6-en-3-one 
• 116546-78-2 (S)-1-benzyloxy-2-methylpentan-3-one 
• 152192-52-4 (S)-2-[(4S,5S,6S)-6-((S)-2-Benzyloxy-1-methyl-ethyl)-2,2-di-tert-butyl-5-methyl-[1,3,2]dioxasilinan-4-yl]-propan-1-ol 

Relevant academic research and scientific papers

The total synthesis of scytophycin C. Part 1: Stereocontrolled synthesis of the C1-C32 protected seco acid

A stereocontrolled synthesis of the C1-C32 seco acid derivative 9 for scytophycin C (1) was completed in 14 steps (18.2% yield, 85% ds) from aldehyde (S)-18. Key steps include: (i) the asymmetric crotylboration of (S)- 18 to give hom

Studies in Polypropionate Synthesis: A General Approach to the Synthesis of Stereopentads.

A general protocol for the synthesis of specific isomers of the stereopentad 1 from the α-chiral ethyl ketones (R)- and (S)-2 has been developed.From (S)-2, this involves stepwise elaboration of each of the three aldol adducts 3, 4 and 5 by stereoselectiv