1409968-66-6

Basic information

• Product Name: C₂₆H₃₁FN₄O₂
• CAS NO: 1409968-66-6
• Molecular Weight: 450.556
• Mol File: 1409968-66-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₂₆H₃₁FN₄O₂(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₆H₃₁FN₄O₂(1409968-66-6)
• EPA Substance Registry System: C₂₆H₃₁FN₄O₂(1409968-66-6)

Safety Data

• Hazardous Substances Data: 1409968-66-6(Hazardous Substances Data)

Upstream product

• 51736-38-0 1-[2(N,N-dimethylamino)ethyl]oxy-2-nitro-benzene 
• 1493-27-2 ortho-nitrofluorobenzene 
• 850895-60-2 2-(2-nitrophenoxy)-1-mesyloxyethane 
• 16365-25-6 2-(2-hydroxyethoxy)nitrobenzene 
• 592552-12-0 C₁₅H₁₇FN₂ 
• 1202-00-2 2-(2'-aminophenoxy)-1-(N,N-dimethylamino)-ethane 
• 7693-46-1 4-Nitrophenyl chloroformate 

Relevant articles and documents

Pyrrolidinyl phenylurea derivatives as novel CCR3 antagonists

Optimization starting with our lead compound 1 (IC50 = 4.9 nM) led to the identification of pyrrolidinyl phenylurea derivatives. Further modification toward improvement of the bioavailability provided (R)-1-(1-((6-fluoronaphthalen-2-yl)methyl)pyrrolidin-3-yl)-3-(2-(2- hydroxyethoxy)phenyl)urea 32 (IC50 = 1.7 nM), a potent and orally active CCR3 antagonist.