1410164-11-2Relevant academic research and scientific papers
Hydrothiolation and intramolecular cyclization sequence for the synthesis of 1,3-oxathiine frameworks
Nishina, Yuta,Miyata, Junya
experimental part, p. 2607 - 2613 (2012/09/07)
1,3-Oxathiine frameworks can be prepared via the sequential addition and intramolecular cyclization of thiosalicylic acid onto alkynes. A substituent on the alkyne and the presence of a palladium catalyst can allow product regioselectivity control. This strategy is applicable to the synthesis of heterocycles comprising sulfur and oxygen atoms, namely 3,1-benzoxathiines, without any unwanted byproduct. Georg Thieme Verlag Stuttgart · New York.
