141045-50-3

Upstream product

• 133678-80-5 (R)-(+)-methyl 4-diazo-2-methyl-2-(4-methylphenyl)-3-oxobutanoate 
• 141116-74-7 (S)-(-)-2-methyl-2-(4-methylphenyl)-4-butanolide 
• 141045-58-1 (R)-(+)-2-methyl-2-(4-methylphenyl)-3-<<(4-methylphenyl)sulfonyl>hydrazono>-4-butanolide 
• 141045-46-7 (S)-(-)-3,3-(ethylenedithio)-2-methyl-2-(4-methylphenyl)-4-butanolide 
• 141045-62-7 (S)-(+)-methyl 2-(chloroformyl)-2-(4-methylphenyl)propionate 
• 133678-83-8 (R)-(+)-2-methyl-2-(4-methylphenyl)-3-oxo-4-butanolide 
• 877077-49-1 (R)-(+)-2-(methoxycarbonyl)-2-(4-methylphenyl)propionic acid 
• 127047-04-5 dimethyl 2-methyl-2-(4-methylphenyl)malonate 
• 79443-97-3 methyl 2-(4-methylphenyl)propanoate 
• 75-16-1 methylmagnesium bromide 
• 105556-92-1 (3S)-2-hydroxy-3-methyl-3-(4-methylphenyl)tetrahydrofuran 

Downstream Products

• 121402-69-5 (S)-(+)-5-methyl-5-(4-methylphenyl)cyclopent-2-en-1-one 
• 141045-52-5 (S)-(+)-3-methyl-3-(4-methylphenyl)-4-oxopentanal 

Relevant academic research and scientific papers

Asymmetric Construction of Quaternary Carbons from Chiral Malonates: Selective and Versatile Total Syntheses of the Enantiomers of α- and β-Cuparenones from a Common Optically Active Precursor

From a single chiron (R)-4, available with high enantiomeric purity (96percent) by simple enzymatic hydrolysis (PLE) of a prochiral malonate, were prepared convenient precursors of the two enantiomers of α- and β-cuparenones (1a,b and 2a,b).This versatile