141108-65-8

Basic information

• Product Name: Octahydropyrazino[2,1-c][1,4]oxazine
• Synonyms: Octahydropyrazino[2,1-c][1,4]oxazine;Octahydropyrazino[2,1-c][1,4]oxazine dihydrochloride;octahydropiperazino[2,1-c]morpholine dihydrochloride
• CAS NO: 141108-65-8
• Molecular Formula: C₇H₁₄N₂O
• Molecular Weight: 142.19886
• Mol File: 141108-65-8.mol
• Article Data: 6

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Octahydropyrazino[2,1-c][1,4]oxazine(CAS DataBase Reference)
• NIST Chemistry Reference: Octahydropyrazino[2,1-c][1,4]oxazine(141108-65-8)
• EPA Substance Registry System: Octahydropyrazino[2,1-c][1,4]oxazine(141108-65-8)

Safety Data

• Hazardous Substances Data: 141108-65-8(Hazardous Substances Data)

Upstream product

• 1383427-85-7 C₁₁H₂₄N₂O₃Si 
• 929047-14-3 C₁₆H₃₂N₂O₅Si 
• 929047-12-1 C₉H₁₉NO₃Si 
• 929047-11-0 C₁₄H₂₇NO₅Si 
• 929047-10-9 hexahydropyrazino[2,1-c][1,4]oxazin-9(6H)-one 
• 212650-43-6 4-(tert-butoxycarbonyl)morpholine-3-carboxylic acid 
• 908066-25-1 hexahydropyrazino[2,1-c][1,4]oxazin-4-one 
• 1126432-05-0 (9aR)-8-(phenylmethyl)octahydropyrazino[2,1-c][1,4]oxazine 

Downstream Products

• 1383453-42-6 C₂₂H₂₄ClFN₄O₄ 
• 1383452-85-4 C₂₁H₂₂ClFN₄O₄ 
• 929046-17-3 2-[3,5-bis(trifluoromethyl)phenyl]-N-[4-(4-fluoro-2-methylphenyl)-6-(hexahydropyrazino[2,1-c][1,4]oxazin-8(1H)-yl)-3-pyridinyl]-N,2-dimethylpropanamide 

Relevant articles and documents

BICYCLIC RING SYSTEM SUBSTITUTED AMIDE FUNCTIONALISED PHENOLS AS MEDICAMENTS

This invention relates to bicyclic ring system substituted amide functionalized phenols of general formula 1, their use as inhibitors of CXCR2 activity, pharmaceutical compositions containing the same, and methods of using the same as agents for treatment and/or prevention of respiratory or gastrointestinal complaints or diseases, inflammatory diseases of the joints, skin, or eyes, diseases of the peripheral or central nervous system or cancers, as well as pharmaceutical compositions which contain these compounds.

BICYCLIC RING SYSTEM SUBSTITUTED SULFONAMIDE FUNCTIONALISED PHENOLS AS MEDICAMENTS

This invention relates to bicyclic ring system substituted sulfonamide functionalized phenols of general formula 1, their use as inhibitors of CXCR2 activity, pharmaceutical compositions containing the same, and methods of using the same as agents for treatment and/or prevention of respiratory or gastrointestinal complaints or diseases, inflammatory diseases of the joints, skin, or eyes, diseases of the peripheral or central nervous system or cancers, as well as pharmaceutical compositions which contain these compounds.

Quinoline derivatives as neurokinin receptor antagonists

The present invention relates to substituted quinoline hydrazides of Formula (I): wherein R1, R2, R3, R4, R5, X, Y and Z are defined herein, pharmaceutical compositions comprising them and their use in treating diseases mediated by neurokinin-2 and/or neurokinin-3 (NK-3) receptors. These compounds can thus be used in methods of treatment to suppress and treat such disorders.