141109-17-3

Usage

Uses

Used in Pharmaceutical Industry:
D(+)-Chloro phenyl glycine methyl ester is used as a chiral building block for the synthesis of various pharmaceuticals. Its unique chiral properties allow for the creation of enantiomerically pure compounds, which are essential in the development of drugs with specific therapeutic effects and reduced side effects.
Used in Agrochemical Industry:
In the agrochemical industry, D(+)-Chloro phenyl glycine methyl ester serves as a key intermediate in the synthesis of agrochemicals, contributing to the development of effective and targeted pest control solutions.
Used in Dye and Pigment Production:
D(+)-Chloro phenyl glycine methyl ester is utilized in the production of certain dyes and pigments, providing a vibrant color palette for various applications, including textiles, plastics, and printing inks.

Upstream product

• 86169-24-6 2-amino-(2-chlorophenyl)ethanoic acid 
• 67-56-1 methanol 

Downstream Products

• 3253-05-2 3-(2-chlorophenyl)pyrazin-2(1H)-one 
• 1352229-31-2 3-(2-chlorophenyl)pyrazine-2(1H)-thione 
• 1352228-90-0 C₁₈H₁₄ClN₃OS 
• 1352228-89-7 C₁₈H₁₃ClFN₃OS 
• 1352228-86-4 C₁₈H₁₃Cl₂N₃OS 
• 1352228-97-7 C₁₈H₁₂Cl₃N₃OS 
• 1352228-87-5 C₁₈H₁₃BrClN₃OS 
• 1352228-88-6 C₁₉H₁₅BrClN₃OS 
• 1352229-01-6 C₁₈H₁₂BrCl₂N₃OS 
• 1352228-93-3 C₂₀H₁₅BrClN₃O₂S 
• 1352228-98-8 C₂₀H₁₅BrClN₃O₃S 
• 1352228-99-9 C₂₁H₁₇BrClN₃O₃S 
• 1352228-92-2 C₁₈H₁₃ClN₄O₃S 
• 1352228-91-1 C₁₉H₁₅ClN₄O₃S 

Relevant academic research and scientific papers

Isotopically Directed Symmetry Breaking and Enantioenrichment in Attrition-Enhanced Deracemization

The evolution of homochirality via attrition-enhanced deracemization (AED) of enantiomorphic solids is carried out using molecules that differ only in the isotopic composition of a phenyl group positioned remote from the chiral center. Enantioenrichment c

Discovery of novel 2-(3-(2-chlorophenyl)pyrazin-2-ylthio)-N-arylacetamides as potent HIV-1 inhibitors using a structure-based bioisosterism approach

The present work is an extension of our ongoing efforts towards the development and identification of new molecules with anti-HIV activity which have previously led to the discovery of arylazolylthioacetanilides as highly active NNRTIs. In this article, a series of 2-2-(3-(2-chlorophenyl)pyrazin-2- ylthio)-N-arylacetamide derivatives were synthesized and evaluated for in vitro anti-HIV activity. Most of the tested compounds exhibited moderate activities against wild-type HIV-1. Among them, compound 6k showed significant activity against wild-type HIV-1 with an EC50 value of 1.7 μM, along with moderate activity against wild-type reverse transcriptase (RT). The preliminary structure-activity relationship (SAR) and docking calculations of this new series of compounds were also investigated, which may help designing more potent molecules.