141189-59-5

Basic information

• Product Name: (3-iodophenyl)-N,N-dimethylmethanamine
• Synonyms: (3-iodophenyl)-N,N-dimethylmethanamine
• CAS NO: 141189-59-5
• Molecular Weight: 261.105
• Mol File: 141189-59-5.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: (3-iodophenyl)-N,N-dimethylmethanamine(CAS DataBase Reference)
• NIST Chemistry Reference: (3-iodophenyl)-N,N-dimethylmethanamine(141189-59-5)
• EPA Substance Registry System: (3-iodophenyl)-N,N-dimethylmethanamine(141189-59-5)

Safety Data

• Hazardous Substances Data: 141189-59-5(Hazardous Substances Data)

Usage

General Description

(3-iodophenyl)-N,N-dimethylmethanamine, also known as 3-Iodo-N,N-dimethylbenzylamine, is a chemical compound with the formula C10H14IN. It is a substituted phenethylamine derivative that is used in the synthesis of various organic compounds. (3-iodophenyl)-N,N-dimethylmethanamine contains an iodine atom attached to a phenyl ring and two methyl groups attached to the nitrogen atom, giving it a unique structure with potential applications in the pharmaceutical and chemical industries. Its precise uses and properties may vary depending on the specific application and context in which it is used.

Upstream product

• 696-41-3 m-iodobenzaldehyde 
• 56553-60-7 sodium tris(acetoxy)borohydride 
• 68-12-2 N,N-dimethyl-formamide 
• 127-19-5 N,N-dimethyl acetamide 
• 100-97-0 hexamethylenetetramine 
• 49617-83-6 m-Iodobenzyl bromide 

Downstream Products

• 1426918-27-5 4-[6-chloro-3-[(E)-2-(3-dimethylaminomethyl-phenyl)-vinyl]-1-(tetrahydro-pyran-2-yl)-1H-pyrazolo[3,4-b]pyridine-4-carbonyl]-piperazine-1-carboxylic acid tert-butyl ester 

Relevant articles and documents

6-(4-Hydroxy-phenyl)-3-styryl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors

The present invention relates to pyrazolo[3,4-b]pyridine compounds of the formula, in which R1, R2, R3, R4 and R5 are defined as indicated below. The compounds of the formula are kinase C (PKC) inhibitors, and are useful for the treatment of diseases associated with diabetes and diabetic complications, such as, diabetic nephropathy, diabetic neuropathy and diabetic retinopathy, for example. The invention furthermore relates to the use of compounds of the formula, in particular as active ingredients in pharmaceuticals, and pharmaceutical compositions comprising them.

6-(4-HYDROXY-PHENYL)-3-STYRYL-1H-PYRAZOLO[3,4-b]PYRIDINE-4-CARBOXYLIC ACID AMIDE DERIVATIVES AS KINASE INHIBITORS

The present invention relates to pyrazolo[3,4-b]pyridine compounds of the formula I, in which R1, R2, R3, R4 and R5 are defined as indicated below. The compounds of the formula I are kinase inhibitors, and are useful for the treatment of diseases associated with diabetes and diabetic complications, such as, diabetic nephropathy, diabetic neuropathy and diabetic retinopathy, for example. The invention furthermore relates to the use of compounds of the formula I, in particular as active ingredients in pharmaceuticals, and pharmaceutical compositions comprising them.