14121-55-2

Usage

Uses

Used in Pharmaceutical Research:
1,2,3,4-tetrahydro-2,3-dioxoquinoxaline-6-carboxylic acid is used as a research compound for exploring its potential pharmacological properties and applications in the pharmaceutical industry. Its presence in the quinoxaline family suggests that it may have therapeutic potential, but further research is needed to understand its specific effects and safety profile.
Used in Chemical Reactions:
1,2,3,4-tetrahydro-2,3-dioxoquinoxaline-6-carboxylic acid is used as a reactive compound in various chemical reactions due to its carbonyl and carboxylic acid groups. These functional groups can participate in a range of reactions, making TDQC a valuable intermediate in the synthesis of other compounds.
Used in Material Science:
1,2,3,4-tetrahydro-2,3-dioxoquinoxaline-6-carboxylic acid is used as a building block in the development of new materials, particularly in the field of organic electronics. Its unique structure and reactivity may contribute to the creation of novel materials with specific properties, such as conductivity or stability.
Used in Analytical Chemistry:
1,2,3,4-tetrahydro-2,3-dioxoquinoxaline-6-carboxylic acid is used as a reference compound or analytical standard in various analytical techniques, such as chromatography or spectroscopy. Its distinct chemical properties can help in the identification and quantification of other compounds in complex mixtures.

InChI:InChI=1/C9H6N2O4/c12-7-8(13)11-6-3-4(9(14)15)1-2-5(6)10-7/h1-3H,(H,10,12)(H,11,13)(H,14,15)

Upstream product

• 144-62-7 oxalic acid 
• 619-05-6 3,4-diaminobenzoic acid 
• 95-92-1 oxalic acid diethyl ester 

Downstream Products

• 1919-43-3 2,3-dichloro-quinoxaline-6-carboxylic acid chloride 
• 17880-88-5 2,3-dichloroquinoxaline-6-carboxylic acid 
• 108229-81-8 2,3-dichloro-quinoxaline-6-carboxylic acid benzyl ester 

Relevant academic research and scientific papers

Bioorthogonal Ligation and Cleavage by Reactions of Chloroquinoxalines with ortho-Dithiophenols

A bioorthogonal ligation and cleavage method via reactions of chloroquinoxalines (CQ) and ortho-dithiophenols (DT) is presented. Double nucleophilic substitutions of ortho-dithiophenols to chloroquinoxalines provide conjugates containing tetracyclic benzo[5,6][1,4]dithiino[2,3-b]quinoxaline with strong built-in fluorescence together with release of the other functional molecules. Three cleavable linkers were designed and successfully used in release of the molecules containing biotin from the protein conjugates. The CQ-DT bioorthogonal reactions can be applied for the bioorthogonal ligations, bioorthogonal cleavages, and trans-tagging of proteins, and show advantages of readily accessible unnatural orthogonal groups, appealing reaction kinetics (k2≈1.3 m?1 s?1), excellent biocompatibility of orthogonal groups, and high stability of conjugates. This complements previous bioorthogonal reactions and is a new route for protein-fishing applications and in-gel fluorescence analysis.

Triketone compound containing quinoxaline structure, and preparation method and application thereof

The invention belongs to the technical field of medicine synthesis, and particularly relates to a triketone compound containing a quinoxaline structure, and a preparation method and an application thereof. The quinoxaline-containing triketone compound has a structure represented by general formula (I). The preparation method is mainly characterized in that a compound with a structure represented by formula (II) is contacted in the presence of an alkali and a solvent, and R1, R2, R3 and R4 in the formulas are respectively defined in the description. The quinoxaline-containing triketone compoundhas high herbicidal activity, and especially has an excellent effect of preventing and controlling broadleaf weeds and/or gramineous weeds, and the prevention and control effect is even better than that of some commercial herbicides sold in the market.