14135-63-8

Basic information

• Product Name: 2-Phenyl-3(2H)-pyridazinone
• Synonyms: 2-Phenyl-3(2H)-pyridazinone;2-phenylpyridazin-3-one;2-Phenyl-3-pyridazinone
• CAS NO: 14135-63-8
• Molecular Formula: C₁₀H₈N₂O
• Molecular Weight: 172.18332
• Mol File: 14135-63-8.mol
• Article Data: 6

Chemical Properties

• Melting Point: 109-110℃
• Boiling Point: 295.9°Cat760mmHg
• Flash Point: 132.8°C
• Appearance: /
• Density: 1.15g/cm³
• Vapor Pressure: 0.00148mmHg at 25°C
• Refractive Index: 1.604
• CAS DataBase Reference: 2-Phenyl-3(2H)-pyridazinone(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Phenyl-3(2H)-pyridazinone(14135-63-8)
• EPA Substance Registry System: 2-Phenyl-3(2H)-pyridazinone(14135-63-8)

Safety Data

• Hazardous Substances Data: 14135-63-8(Hazardous Substances Data)

Usage

Synthesis Reference(s)

Synthetic Communications, 21, p. 1021, 1991 DOI: 10.1080/00397919108019791

InChI:InChI=1/C10H8N2O/c13-10-7-4-8-11-12(10)9-5-2-1-3-6-9/h1-8H

Upstream product

• 166328-14-9 potassium (furan-2-yl)trifluoroboranuide 
• 369-57-3 benzenediazonium tetrafluoroborate 
• 1698-54-0 6-hydroxy-2-phenyl-3(2H)-pyridazinone 
• 504-30-3 2H-Pyridazin-3-one 
• 591-50-4 iodobenzene 
• 83297-09-0 5-(1,2-diaza-1-phenylbutadien-4-ylidene)-2,2-dimethyl-1,3-dioxan-4,6-dione 
• 4071-88-9 trimethylsilanyl-acetic acid ethyl ester 
• 20672-18-8 2-(phenylhydrazono)ethanal 
• 867-13-0 diethoxyphosphoryl-acetic acid ethyl ester 
• 130472-36-5 N'-[(E)-3-Ethoxycarbonyl-prop-2-en-(Z)-ylidene]-N,N,N-trimethyl-hydrazinium; iodide 
• 100-63-0 phenylhydrazine 
• 1698-57-3 6-chloro-2-phenylpyridazine-3(2H)-one 

Downstream Products

• 143998-65-6 2-Phenyl-5-(toluene-4-sulfonylmethyl)-2H-pyridazin-3-one 
• 143998-63-4 2-Phenyl-4-(toluene-4-sulfonylmethyl)-2H-pyridazin-3-one 
• 143998-67-8 3-Phenyl-7-(toluene-4-sulfonyl)-3,4-diaza-bicyclo[4.1.0]hept-4-en-2-one 

Relevant articles and documents

A new mild synthetic route to N-arylated pyridazinones from aryldiazonium salts

An efficient method for the synthesis of N-arylated pyridazinones from potassium 2-furantrifluoroborate and aryldiazonium salts is described. The reaction was run in water at 0-5 °C in short reaction times and without any catalyst or additive. A mechanistic proposal is made based on the experimental data and DFT calculations. the Partner Organisations 2014.

A new and convenient synthesis of 3(2H)-pyridazinones by reacting carbanion of ethyl trimethylsilylacetate with phenylhydrazones

A one-pot synthesis of 5,6-disubstituted-2-phenyl-3(2H)-pyridazinones 4 is achieved on treatment of carbanion of ethyl trimethylsilylacetate with phenylhydrazones of 1,2-dicarbonyl compounds 1.

(E)-Ethyl β-formylacrylate Dimethylhydrazone Methiodide: a Reactive and Convenient Precursor of (E)-Ethyl-β-formylacrylate

The methiodide of (E)-Ethyl-β-formylacrylate dimethylhydrazone is readily prepared in two steps.It gives rise to regioselective 1,4-additions and is a stable and convenient precursor of (E)-Ethyl-β-formylacrylate.