141407-30-9Relevant academic research and scientific papers
Sulfonyl chloride as a disposable electron withdrawing substituent in halex fluorinations
Kageyama, Hiroyuki,Suzuki, Hiroshi,Kimura, Yoshikazu
, p. 85 - 89 (2000)
Syntheses of 1,3-difluorobenzene and 2,6-difluorotoluene are described via chlorosulfonation, catalytic Halex-fluorination, and desulfination of 1,3-dichlorobenzene and 2,6-dichlorotoluene.
Tetraphenylphosphonium bromide-catalyzed 'Halex' fluorination of chloroaryl sulfonyl chlorides
Suzuki, Hiroshi,Kageyama, Hiroyuki,Yoshida, Yasuo,Kimura, Yoshikazu
, p. 335 - 337 (2007/10/02)
Halogen-exchange of chloroaryl sulfonylchloride derivatives with spray-dried potassium fluoride was found to proceed efficiently by employing tetraphenylphosphonium bromide as a catalyst.Subsequent desulfonylation of the fluoroaryl sulfonyl derivatives readily afforded fluoroaromatics under acidic condition.
