141417-89-2

Upstream product

• 68-12-2 N,N-dimethyl-formamide 
• 122-51-0 orthoformic acid triethyl ester 
• 371-40-4 4-fluoroaniline 
• 77287-34-4 formamide 
• 370-22-9 N,N'-Di-(4-Fluorphenyl)-harnstoff 

Downstream Products

• 130685-65-3 4-Cyan-3-(4-fluor-phenylamino)-benzo<4,5>thieno<2,3-c>pyridin-9,9-dioxid 
• 130686-21-4 2-(4-Fluor-anilinomethylen)-2,3-dihydro-3-oxo-benzo-thiophen-1,1-dioxid 
• 130685-55-1 2-(4-Fluor-anilinomethylen)-2,3-dihydro-3-oxo-benzo-thiophen-1,1-dioxid 
• 73169-51-4 Re(CO)4CH(NC₆H₄F)2 
• 1356826-84-0 [Au(4-FC₆H₄N)2CH]4 

Relevant academic research and scientific papers

Structures, Electronics, and Reactivity of Strained Phosphazane Cages: A Combined Experimental and Computational Study

A series of formamidine-bridged P2N2 cages have been prepared. Upon deprotonation, these compounds serve as valuable precursors to hybrid N-heterocyclic carbene ligands, whereas direct metalation gives rearranged dimetallic complexes as a result of cleavage of the formamidine bridge. The latter metal complexes contain an intact cyclophosphazane moiety that coordinates two distinct metal centers in a monodentate and a chelating fashion. A computational study has been carried out to elucidate the bonding within the P2N2 framework as well as the reactivity patterns. Natural bond orbital analysis indicates that the cage motif is poorly described by localized Lewis structures and that negative hyperconjugation effects govern the stability of the bicyclic framework. The donor capacity of the cyclophosphazane unit was assessed by inspection of the frontier molecular orbitals, highlighting the fact that π-back-donation from the metal fragments is crucial for effective metal-ligand binding.

Method For Preparing Formamidines

A method for preparing formamidines of formula (I) in a single step by reducing ureas of formula (II) using silanes of formula (III), according to reaction (II)+(III)+(I) is provided. The present invention also provides a method for preparing insecticides

Pushing back the limits of hydrosilylation: Unprecedented catalytic reduction of organic ureas to formamidines

Pushing back the limits: A novel catalytic transformation has been designed to prepare formamidine derivatives by reduction of substituted ureas with hydrosilanes. Simple iron catalysts based on commercially available iron salts and phosphine ligands prov

Ultrasound promoted expeditious, catalyst-free and solvent-free approach for the synthesis of N,N′-diarylsubstituted formamidines at room temperature

An effortless and efficient protocol was developed for the synthesis of N,N′-diarylsubstituted formamidines under environment-friendly conditions. Ultrasonic energy was employed to obtain the desired products in excellent yields with high purity under solvent-free and catalyst-free conditions. Products were purified by the crystallization technique to avoid excess utilization of organic solvents.

Multicomponent synthesis of 1-aryl 1,2,4-triazoles

A multicomponent (single reactor) process for the synthesis of 1-aryl 1,2,4-triazoles was explored and developed. This transformation prepared the 1,2,4-triazole directly from anilines, amino pyridines, and pyrimidines. The reaction scope was explored with 21 different substrates, and the position of the nitrogen atoms in the newly formed ring was established by 15N labeling and NMR spectroscopy.

Evaluation of electrophilic heteroaromatic substitution: Synthesis of heteroaromatic-fused pyrimidine derivatives via sequential three-component heterocyclization

A new sequential three-component heterocyclization was developed by reacting aromatic and heterocyclic substrates, including aminobenzenes, 1-aminonaphthalene, 2-aminopyrazines, 5-aminopyrazoles, 3-aminopyridine, 5-aminopyrimidine, 5-aminoquinoline, and 8

A new and green synthesis of formamidines by γ-Fe2O 3@SiO2-HBF4 nanoparticles as a robust and magnetically recoverable catalyst

A series of Bronsted acids (HA) were immobilized on superparamagnetic γ-Fe2O3@SiO2. The synthesized [γ-Fe2O3@SiO2-HA] nanocrystallites were fully characterized by spectroscopic techniques (FT-IR, XRD, SEM, EDX) and used as solid acid catalysts in the synthesis of biologically important formamidines. The results were excellent in yield and time of reaction. Activity of various Bronsted acids on superparamagnetic support as catalyst were also evaluated and among them immobilized HBF4 showed the best catalytic properties.

Biomimetic approach for the synthesis of N,N′-diarylsubstituted formamidines catalyzed by β-cyclodextrin in water

An environmentally benign and highly efficient biomimetic approach for the synthesis of N,N′-diarylsubstituted formamidines in water catalyzed β-cyclodextrin is described under neutral condition with quantitative yields of products. β-Cyclodextrin has bee

Fine-tuning the luminescence and HOMO-LUMO energy levels in tetranuclear gold(I) fluorinated amidinate complexes

Tetranuclear gold(I) fluorinated amidinate complexes have been synthesized and their photophysical properties and structures described. DFT calculations were carried out to illustrate how a minor change in the ligand resulted in a loss of emission in the

Reactions of Aryliminodimagnesium with Some N,N-Dimethylcarboxamides and Benzonitriles Affording Various Types of Amidines. Correction of Previous Results on Formamidine Formation from N,N-Dimethylformamide

Some symmetrical and unsymmetrical form- and benzamidines were prepared by the reaction of ArN(MgBr)2 with Ar'CN, HCONMe2 and related compounds in tetrahydrofuran.