1414889-16-9

Basic information

• Product Name: (R)-1-(4-methoxybenzyl)-2-oxo-4,6-bis(trifluoromethyl)-1,2,3,4-tetrahydroquinazoline-4-carbonitrile
• Synonyms: (R)-1-(4-methoxybenzyl)-2-oxo-4,6-bis(trifluoromethyl)-1,2,3,4-tetrahydroquinazoline-4-carbonitrile
• CAS NO: 1414889-16-9
• Molecular Weight: 429.322
• Mol File: 1414889-16-9.mol

Chemical Properties

• CAS DataBase Reference: (R)-1-(4-methoxybenzyl)-2-oxo-4,6-bis(trifluoromethyl)-1,2,3,4-tetrahydroquinazoline-4-carbonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-1-(4-methoxybenzyl)-2-oxo-4,6-bis(trifluoromethyl)-1,2,3,4-tetrahydroquinazoline-4-carbonitrile(1414889-16-9)
• EPA Substance Registry System: (R)-1-(4-methoxybenzyl)-2-oxo-4,6-bis(trifluoromethyl)-1,2,3,4-tetrahydroquinazoline-4-carbonitrile(1414889-16-9)

Safety Data

• Hazardous Substances Data: 1414889-16-9(Hazardous Substances Data)

Upstream product

• 7677-24-9 trimethylsilyl cyanide 
• 1414889-30-7 C₁₈H₁₂F₆N₂O₂ 

Relevant articles and documents

Highly enantioselective organocatalytic Strecker reaction of cyclic N-acyl trifluoromethylketimines: Synthesis of anti-HIV drug DPC 083

A highly efficient, organocatalytic, enantioselective Strecker reaction of cyclic N-acyl ketimines was developed for the preparation of enantioenriched cyclic α-amino nitriles with a quaternary carbon stereocentre and anti-HIV drug DPC 083. This journal is

Highly enantioselective organocatalytic Strecker reaction of cyclic N-acyl trifluoromethylketimines: Synthesis of anti-HIV drug DPC 083

A highly efficient, organocatalytic, enantioselective Strecker reaction of cyclic N-acyl ketimines was developed for the preparation of enantioenriched cyclic α-amino nitriles with a quaternary carbon stereocentre and anti-HIV drug DPC 083. The Royal Society of Chemistry 2012.