1414932-59-4

Basic information

• Product Name: 1-(1-benzyl-1H-tetrazol-5-yl)-1,2,3,4-tetrahydronaphthalen-1-ol
• Synonyms: 1-(1-benzyl-1H-tetrazol-5-yl)-1,2,3,4-tetrahydronaphthalen-1-ol
• CAS NO: 1414932-59-4
• Molecular Weight: 306.367
• Mol File: 1414932-59-4.mol

Chemical Properties

• CAS DataBase Reference: 1-(1-benzyl-1H-tetrazol-5-yl)-1,2,3,4-tetrahydronaphthalen-1-ol(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(1-benzyl-1H-tetrazol-5-yl)-1,2,3,4-tetrahydronaphthalen-1-ol(1414932-59-4)
• EPA Substance Registry System: 1-(1-benzyl-1H-tetrazol-5-yl)-1,2,3,4-tetrahydronaphthalen-1-ol(1414932-59-4)

Safety Data

• Hazardous Substances Data: 1414932-59-4(Hazardous Substances Data)

Upstream product

• 79344-08-4 1-benzyl-5-bromo-1H-tetrazole 
• 529-34-0 3,4-dihydronaphthalene-1(2H)-one 
• 100-46-9 benzylamine 
• 6926-50-7 1-benzyl-1H-tetrazole 

Relevant articles and documents

Some practical methods for the application of 5-metallo-1-benzyl-1H- tetrazoles in synthesis

Nucleophilic reagents such as 5-lithiotetrazoles are synthetically powerful tools for the installation of tetrazole functional groups, but they are of limited utility due to the instability of tetrazole-derived carbanions. Herein, we report practical methods for the generation and use of new 5-metallo-1-benzyl-1H-tetrazoles (M=K, MgX, ZnX) derived from either 1-benzyl-1H-tetrazole or 1-benzyl-5-bromo-1H-tetrazole. By varying the metal counterion, the tetrazole carbanion stability was improved. Potassium- and magnesium-derived reagents underwent additions to carbonyl compounds at -30 and -20°C, respectively. The isolated yields (41-85%) from these and other reactions were comparable to those reported for 5-lithiotetrazoles at much lower temperatures (-78 to -98 °C). Georg Thieme Verlag Stuttgart ? New York.