1415129-75-7

Upstream product

• 1679-18-1 4-Chlorophenylboronic acid 
• 6911-87-1 4-bromo-N-methylaniline 
• 29682-15-3 methyl 5-bromopicolinate 
• 148839-33-2 (5-chloro-2-methylphenyl)boronic acid 
• 115647-48-8 4'-chloro-N-methyl-[1,1'-biphenyl]-4-amine 
• 1415129-66-6 methyl 5-(5-chloro-2-methylphenyl)picolinate 
• 1415129-69-9 methyl 5-(2-(bromomethyl)-5-chlorophenyl)picolinate 
• 1415129-72-4 methyl 5-(5-chloro-2-(((4'-chloro-[1,1'-biphenyl]-4-yl)(methyl)amino)methyl)phenyl)picolinate 

Downstream Products

• 1415129-78-0 ethyl 3-(5-(5-chloro-2-(((4'-chloro-[1,1'-biphenyl]-4-yl)(methyl)amino)methyl)phenyl)picolinamido)propanoate 
• 1415127-53-5 3-(5-(5-chloro-2-(((4'-chloro-[1,1'-biphenyl]-4-yl)(methyl)amino)methyl)phenyl)picolinamido)propanoic acid 

Relevant academic research and scientific papers

PICOLINAMIDO-PROPANOIC ACID DERIVATIVES USEFUL AS GLUCAGON RECEPTOR ANTAGONISTS

The present invention is directed to picolanmido-propanoic acid derivatives, pharmaceutical compositions containing them and their use in the treatment and/or prevention of disorders and conditions ameliorated by antagonizing one or more glucagon receptors, including for example metabolic diseases such as Type II diabetes mellitus and obesity.