1415310-29-0

Basic information

• Product Name: 2-{2-[(1R,2R)-1-(2-chlorobenzyl)-2-ethoxycarbonyl-2-hydroxyethylcarbamoyl]pyridin-4-yl}benzoic acid ethyl ester trifluoroacetic acid salt
• Synonyms: 2-{2-[(1R,2R)-1-(2-chlorobenzyl)-2-ethoxycarbonyl-2-hydroxyethylcarbamoyl]pyridin-4-yl}benzoic acid ethyl ester trifluoroacetic acid salt
• CAS NO: 1415310-29-0
• Molecular Weight: 624.998
• Mol File: 1415310-29-0.mol

Chemical Properties

• CAS DataBase Reference: 2-{2-[(1R,2R)-1-(2-chlorobenzyl)-2-ethoxycarbonyl-2-hydroxyethylcarbamoyl]pyridin-4-yl}benzoic acid ethyl ester trifluoroacetic acid salt(CAS DataBase Reference)
• NIST Chemistry Reference: 2-{2-[(1R,2R)-1-(2-chlorobenzyl)-2-ethoxycarbonyl-2-hydroxyethylcarbamoyl]pyridin-4-yl}benzoic acid ethyl ester trifluoroacetic acid salt(1415310-29-0)
• EPA Substance Registry System: 2-{2-[(1R,2R)-1-(2-chlorobenzyl)-2-ethoxycarbonyl-2-hydroxyethylcarbamoyl]pyridin-4-yl}benzoic acid ethyl ester trifluoroacetic acid salt(1415310-29-0)

Safety Data

• Hazardous Substances Data: 1415310-29-0(Hazardous Substances Data)

Upstream product

• 1415312-56-9 (2R,3R)-3-[(4-bromo-pyridine-2-carbonyl)-amino]-4-(2-chloro-phenyl)-2-hydroxy-butyric acid ethyl ester 
• 76-05-1 trifluoroacetic acid 
• 269409-99-6 ethyl 2-(4,4,5,5-tetramethyl[1,3,2]dioxaborolan-2-yl)benzoate 
• 80126-50-7 (R)-2'-chlorophenylalanine 
• 1415312-30-9 (2R,3R)-3-Amino-4-(2-chloro-phenyl)-2-hydroxy-butyric acid ethyl ester 
• 1415312-26-3 [(R)-1-(2-chloro-benzyl)-2-cyano-2-hydroxy-ethyl]-carbamic acid benzyl ester 
• 1270301-63-7 C₁₇H₁₆ClNO₄ 
• 1415312-22-9 C₁₉H₂₁ClN₂O₄ 
• 1415312-24-1 C₁₇H₁₆ClNO₃ 

Relevant articles and documents

NEPRILYSIN INHIBITORS

In one aspect, the invention relates to compounds having the formula: where R1, R2, R3, X, R4, R5, and R6 are as defined in the specification, or a pharmaceutically acceptable salt thereof. These compounds have neprilysin inhibition activity. In another aspect, the invention relates to pharmaceutical compositions comprising such compounds; methods of using such compounds; and process and intermediates for preparing such compounds.