1415312-22-9

Basic information

• Product Name: C₁₉H₂₁ClN₂O₄
• Synonyms: C₁₉H₂₁ClN₂O₄
• CAS NO: 1415312-22-9
• Molecular Weight: 376.84
• Mol File: 1415312-22-9.mol

Chemical Properties

• CAS DataBase Reference: C₁₉H₂₁ClN₂O₄(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₉H₂₁ClN₂O₄(1415312-22-9)
• EPA Substance Registry System: C₁₉H₂₁ClN₂O₄(1415312-22-9)

Safety Data

• Hazardous Substances Data: 1415312-22-9(Hazardous Substances Data)

Upstream product

• 80126-50-7 (R)-2'-chlorophenylalanine 
• 13139-17-8 N-(Benzyloxycarbonyloxy)succinimide 
• 1270301-63-7 C₁₇H₁₆ClNO₄ 
• 6638-79-5 N,O-dimethylhydroxylamine*hydrochloride 

Downstream Products

• 1415312-28-5 (2R,3R)-3-Amino-4-(2-chloro-phenyl)-2-hydroxy-butyric acid Methyl Ester 
• 1415312-52-5 (2R,3S)-3-amino-4-(2-chloro-phenyl)-2-hydroxy-butyric acid methyl ester 
• 1415312-30-9 (2R,3R)-3-Amino-4-(2-chloro-phenyl)-2-hydroxy-butyric acid ethyl ester 
• 1415312-54-7 (2R,3S)-3-amino-4-(2-chloro-phenyl)-2-hydroxy-butyric acid ethyl ester 
• 1415312-26-3 [(R)-1-(2-chloro-benzyl)-2-cyano-2-hydroxy-ethyl]-carbamic acid benzyl ester 
• 1415312-24-1 C₁₇H₁₆ClNO₃ 
• 1415481-68-3 (2R,3R)-3-amino-4-(2-chloro-phenyl)-2-hydroxy-butyric acid butyl ester hydrochloride 
• 1415481-70-7 2-{3-[(1R,2R)-2-butoxycarbonyl-1-(2-chloro-benzyl)-2-hydroxy-ethylcarbamoyl]-propyl}-benzoic acid 
• 1415481-71-8 2-{3-[(1R,2R)-1-(2-chlorobenzyl)-2-ethoxycarbonyl-2-hydroxy-ethylcarbamoyl]-propyl}-benzoic acid 
• 1415481-69-4 2-{3-[(1R,2R)-2-carboxy-1-(2-chloro-benzyl)-2-hydroxy-ethylcarbamoyl]-propyl}-benzoic acid 
• 1415481-75-2 5'-[(1R,2R)-2-carboxy-1-(2-chlorobenzyl)-2-hydroxy-ethylcarbamoyl]-2',3'-difluoro-biphenyl-2-carboxylic acid 
• 1415481-83-2 (2R,3R)-4-(2-chlorophenyl)-2-hydroxy-3-[4-(3-methyl-5-oxo-4,5-dihydro-pyrazol-1-yl)-benzoylamino]-butyric acid 
• 1415310-29-0 2-{2-[(1R,2R)-1-(2-chlorobenzyl)-2-ethoxycarbonyl-2-hydroxyethylcarbamoyl]pyridin-4-yl}benzoic acid ethyl ester trifluoroacetic acid salt 
• 1415312-55-8 2-{2-[(1R,2R)-1-(2-chlorobenzyl)-2-ethoxycarbonyl-2-hydroxyethylcarbamoyl]pyridin-4-yl}benzoic acid t-butyl ester 

Relevant articles and documents

NEPRILYSIN INHIBITORS

In one aspect, the invention relates to compounds having the formula: where R1, R2, R3, a, R4, R5, and R6 are as defined in the specification, or a pharmaceutically acceptable salt thereof. These compounds have neprilysin inhibition activity. In another aspect, the invention relates to pharmaceutical compositions comprising such compounds; methods of using such compounds; and process and intermediates for preparing such compounds.

NEPRILYSIN INHIBITORS

In one aspect, the invention relates to compounds having the formula: where R1, R2, R3, X, R4, R5, and R6 are as defined in the specification, or a pharmaceutically acceptable salt thereof. These compounds have neprilysin inhibition activity. In another aspect, the invention relates to pharmaceutical compositions comprising such compounds; methods of using such compounds; and process and intermediates for preparing such compounds.

NEPRILYSIN INHIBITORS

In one aspect, the invention relates to compounds having the formula: where R1, R2, R3, R4, and R5 are as defined in the specification, or a pharmaceutically acceptable salt thereof. These compounds have neprilysin inhibition activity. In another aspect, the invention relates to pharmaceutical compositions comprising such compounds; methods of using such compounds; and process and intermediates for preparing such compounds.