1415310-39-2

Upstream product

• 98525-68-9 ethyl 2-(2-(but-3-en-1-yl)-1,3-dioxolan-2-yl)acetate 
• 17605-06-0 ethyl 3-oxohept-6-enoate 
• 1006058-88-3 (S)-2-(benzyloxy)-5-(tert-butyldiphenylsilyloxy)pentanal 
• 1415310-22-3 ((S)-4-(benzyloxy)-5-((R)-p-tolylsulfinyl)pentyloxy)(tert-butyl)diphenylsilane 
• 1415310-21-2 (S)-5-(tert-butyldiphenylsilyloxy)-1-((R)-p-tolylsulfinyl)pentan-2-ol 
• 591-80-0 pent-4-enoic acid 
• 1415310-20-1 (R)-5-(tert-butyldiphenylsilyloxy)-1-(p-tolylsulfinyl)pentan-2-one 
• 179690-96-1 methyl 4-[[(1,1-dimethylethyl)diphenylsilyl]oxy]butanoate 
• 1415310-33-6 (4S,5S)-5-(benzyloxy)-2-8-(tert-butyldiphenylsilyloxy)oct-1-en-4-ol 
• 1415310-30-3 (4S,6S)-6-(but-3-enyl)-N-methoxy-N,2,2-trimethyl-1,3-dioxane-4-carboxamide 
• 1415310-36-9 C₃₇H₅₃BrO₃Si₂ 
• 1415310-27-8 C₁₁H₁₈O₃ 
• 1415310-84-7 C₁₈H₂₆O₃S 
• 1415310-24-5 C₁₅H₂₂O₃S 

Relevant academic research and scientific papers

Diastereoselective synthesis of the C17-C30 fragment of amphidinol 3

The diastereoselective synthesis of the C17-C30 fragment of amphidinol 3 (AM3) 1 was achieved from the enantio-enriched aldehyde 20, Weinreb amide 14 and 2-bromo-3-(trimethylsilyl)propene, which was used as a bifunctional conjunctive reagent. The absolute configuration of the stereogenic centers, in both aldehyde 20 and Weinreb amide 14, were efficiently controlled by using (+)-(R)-methyl-p-tolylsulfoxide as the unique source of chirality.