1415336-41-2Relevant academic research and scientific papers
Studies toward the synthesis of potent anti-inflammatory peptides solomonamides A and B: Synthesis of a macrocyclic skeleton and key fragment 4-amino-6-(2′-amino-4′-hydroxyphenyl)-3-hydroxy-2-methyl-6- oxohexanoic acid (AHMOA)
Kashinath,Vasudevan,Reddy, D. Srinivasa
, p. 6222 - 6225 (2013/02/23)
A first synthetic effort toward total synthesis of highly potent solomonamides is disclosed. An efficient strategy to synthesize this class of compounds, along with the synthesis of a core macrocycle (shown in red) and the key fragment AHMOA, is described.
