141546-74-9

Upstream product

• 169898-61-7 (+/-)-5-(4-methoxyphenyl)-2-methyl-3-oxo-(4E)-penten-1-ol 
• 150932-10-8 (2S,3S)-3-methoxy-5-(4-methoxyphenyl)-2-methyl-(4E)-penten-1-ol 
• 153899-36-6 (E)-(3S,4R)-4-Methoxy-6-(4-methoxy-phenyl)-3-methyl-hex-5-enal 
• 141546-68-1 4-O-benzoyl-2-deoxy-1-O-methylsulfonyl-2-C-methyl-3-O-methyl-L-threitol 
• 153899-35-5 Benzoic acid (2R,3R)-2-methoxy-3-methyl-4-oxo-butyl ester 
• 141546-66-9 1,6-di-O-benzoyl-3-deoxy-3-C-methyl-2-O-methyl-L-altritol 
• 141546-69-2 (3S,4R)-5-benzyloxy-4-methoxy-3-methylpentanenitrile 
• 141546-67-0 4-O-benzoyl-2-deoxy-2-C-methyl-3-O-methyl-L-threitol 
• 141546-71-6 (3S,4R)-4-Methoxy-3-methyl-5-oxo-pentanenitrile 
• 141546-70-5 (3S,4R)-5-hydroxy-4-methoxy-3-methylpentanenitrile 
• 170081-25-1 (2S,3S)-1-tert-butyldimethylsiloxy-3-methoxy-5-(4-methoxyphenyl)-2-methyl-(4E)-pentene 
• 170081-24-0 (2S,3S)-1-tert-butyldimethylsiloxy-3-hydroxy-5-(4-methoxyphenyl)-2-methyl-(4E)-pentene 
• 151121-11-8 (2S,3S)-5-(4-methoxyphenyl)-2-methyl-(4E)-penten-1,3-diol 
• 141546-73-8 (E)-(3S,4R)-4-methoxy-6-(4-methoxyphenyl)-3-methylhex-5-enenitrile 

Downstream Products

• 153899-38-8 (E)-(3S,4S)-2-[1-Hydroxy-meth-(E)-ylidene]-4-methoxy-6-(4-methoxy-phenyl)-3-methyl-hex-5-enoic acid methyl ester 
• 130640-32-3 (-)-oudemansin X 

Relevant academic research and scientific papers

Total synthesis of (±)-, (-)-, and (+)-oudemansin X

Three kinds of oudemansin X, (-)-1, (+)-1 and (±)-1, were totally synthesized. The key point in the present chiral synthesis was the enantioselective acetylation of the racemic alcohols, (±)-5 and (±)-8, using lipase in an organic solvent. The synthetic (-)-1 was found to exhibit strong antifungal activity against several molds and yeasts.

Utilisation of L-Quebrachitol in Natural Product Synthesis. Total Synthesis and Absolute Configuration of (-)-Oudemansin X

The stereoselective conversion of the naturally occurring optically active cyclitol, L-quebrachitol 2, into antifungal β-methoxyacrylate, oudemansin X 1 is described.The first total synthesis of 1 fully confirmed the proposed absolute configuration of the