169898-61-7

Upstream product

• 24680-50-0 4-methoxy-trans-cinnamaldehyde 
• 126753-78-4 methyl 5-(4-methoxyphenyl)-2-methyl-3-oxopent-4-enoate 

Downstream Products

• 141546-73-8 (E)-(3S,4R)-4-methoxy-6-(4-methoxyphenyl)-3-methylhex-5-enenitrile 
• 153899-37-7 (E)-(3S,4R)-4-Methoxy-6-(4-methoxy-phenyl)-3-methyl-hex-5-enoic acid 
• 141546-74-9 methyl (E)-(3S,4R)-4-methoxy-6-(4-methoxyphenyl)-3-methylhex-5-enoate 
• 130640-32-3 (-)-oudemansin X 
• 150932-10-8 (2S,3S)-3-methoxy-5-(4-methoxyphenyl)-2-methyl-(4E)-penten-1-ol 
• 150932-09-5 (2R,3R)-1-acetoxy-3-hydroxy-5-(4-methoxyphenyl)-2-methyl-(4E)-pentene 
• 151121-11-8 (2S,3S)-5-(4-methoxyphenyl)-2-methyl-(4E)-penten-1,3-diol 
• 169531-50-4 (2R,3R)-5-(4-methoxyphenyl)-2-methyl-(4E)-penten-1,3-diol 
• 170081-26-2 (2R,3R)-3-methoxy-5-(4-methoxyphenyl)-2-methyl-(4E)-penten-1-ol 
• 163037-42-1 (2R,3R)-1-acetoxy-3-methoxy-5-(4-methoxyphenyl)-2-methyl-(4E)-pentene 

Relevant academic research and scientific papers

Total synthesis of (-)-oudemansin X based on enzymatic resolution using immobilized lipase

(-)-Oudemansin X (1) was synthesized based on enzymatic resolution of (±)-diol 5 using immobilized lipase.

Total synthesis of (±)-, (-)-, and (+)-oudemansin X

Three kinds of oudemansin X, (-)-1, (+)-1 and (±)-1, were totally synthesized. The key point in the present chiral synthesis was the enantioselective acetylation of the racemic alcohols, (±)-5 and (±)-8, using lipase in an organic solvent. The synthetic (-)-1 was found to exhibit strong antifungal activity against several molds and yeasts.