1415648-01-9Relevant academic research and scientific papers
Multicomponent synthesis of 4-aminophthalazin-1(2 H)-ones by palladium-catalyzed isocyanide insertion
Vlaar, Tjostil,Mampuys, Pieter,Helliwell, Madeleine,Maes, Bert U. W.,Orru, Romano V. A.,Ruijter, Eelco
, p. 6735 - 6745 (2013/07/26)
4-Aminophthalazin-1(2H)-ones (APOs) are underexplored heterocyclic compounds with promising and diverse biological activities. The classical synthesis of these compounds is tedious and does not allow the regioselective introduction of substituents. Here,
Facile synthesis of novel 7-aminofuro- and 7-aminothieno[2,3-d]pyridazin- 4(5H)-one and 4-aminophthalazin-1(2H)-ones
Koza, Gani,Keskin, Selbi,?zer, Merve Sinem,Cengiz, Betül,?ahin, Ertan,Balci, Metin
, p. 395 - 409 (2013/01/15)
We hereby report the synthesis of a novel class of compounds, 7-aminofuro- and 7-aminothieno[2,3-d]pyridazin-4(5H)-one and 4-aminophthalazin-1(2H)-ones starting from methyl 2-(2-methoxy-2-oxoethyl)furan- and thiophene-3-carboxylate and methyl 2-(2-methoxy
