1415757-40-2

Basic information

• Product Name: (R)-2-{3-fluoro-4-[(6-fluoro-1H-indazole-3-carbonyl)-amino]-phenyl}-morpholine-4-carboxylic acid tert-butyl ester
• Synonyms: (R)-2-{3-fluoro-4-[(6-fluoro-1H-indazole-3-carbonyl)-amino]-phenyl}-morpholine-4-carboxylic acid tert-butyl ester
• CAS NO: 1415757-40-2
• Molecular Weight: 458.465
• Mol File: 1415757-40-2.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (R)-2-{3-fluoro-4-[(6-fluoro-1H-indazole-3-carbonyl)-amino]-phenyl}-morpholine-4-carboxylic acid tert-butyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-2-{3-fluoro-4-[(6-fluoro-1H-indazole-3-carbonyl)-amino]-phenyl}-morpholine-4-carboxylic acid tert-butyl ester(1415757-40-2)
• EPA Substance Registry System: (R)-2-{3-fluoro-4-[(6-fluoro-1H-indazole-3-carbonyl)-amino]-phenyl}-morpholine-4-carboxylic acid tert-butyl ester(1415757-40-2)

Safety Data

• Hazardous Substances Data: 1415757-40-2(Hazardous Substances Data)

Upstream product

• 695188-21-7 4-bromo-3-fluorobenzoyl chloride 
• 1260857-14-4 2-chloro-1-(4-bromo-3-fluorophenyl)-ethanone 
• 1400997-35-4 (RS)-2-(4-bromo-3-fluorophenyl)-oxirane 
• 1400997-36-5 (RS)-1-(4-bromo-3-fluorophenyl)-2-(2-hydroxyethylamino)-ethanol 
• 1400997-38-7 (RS)-2-(4-bromo-3-fluorophenyl)-morpholine-4-carboxylic acid tert-butyl ester 
• 1400997-39-8 (RS)-2-[4-(benzhydrylideneamino)-3-fluorophenyl]-morpholine-4-carboxylic acid tert-butyl ester 
• 1400997-40-1 (RS)-2-(4-amino-3-fluorophenyl)-morpholine-4-carboxylic acid tert-butyl ester 
• 1400997-47-8 (+)-(R)-2-(4-amino-3-fluorophenyl)-morpholine-4-carboxylic acid tert-butyl ester 
• 129295-30-3 6-fluoro-1H-indazole-3-carboxylic acid 

Downstream Products

• 1415756-03-4 6-fluoro-1H-indazole-3-carboxylic acid ((R)-2-fluoro-4-morpholin-2-yl-phenyl)amide 

Relevant articles and documents

SUBSTITUTED BENZAMIDE DERIVATIVES

The present invention relates to compounds of formula wherein R1, R2, R3, X, Z, Ar, and n are as described in the claims, Ar is phenyl or heteroaryl, selected from the group consisting of 1H-indazole-3yl, pyridine-2-yl, pyridine-3-yl, pyridine-4-yl, pyrimidine-5-yl, 1H-pyrazole-3-yl, 1H-pyrazole-4-yl and 1H-pyrazole-5-yl; or to a pharmaceutically suitable acid addition salt thereof, which may be used for the treatment of depression, anxiety disorders, bipolar disorder, attention deficit hyperactivity disorder (ADHD), stress-related disorders, psychotic disorders, schizophrenia, neurological diseases, Parkinson's disease, neurodegenerative disorders, Alzheimer's disease, epilepsy, migraine, hypertension, substance abuse, metabolic disorders, eating disorders, diabetes, diabetic complications, obesity, dyslipidemia, disorders of energy consumption and assimilation, disorders and malfunction of body temperature homeostasis, disorders of sleep and circadian rhythm, and cardiovascular disorders.