14161-11-6

Basic information

• Product Name: 3,4,5-TRICHLOROPYRIDAZINE
• Synonyms: 3,4,5-TRICHLOROPYRIDAZINE;3,4,5-TRICHLOROPYRIDAZINE 98%;Einecs 238-006-2;Nsc 75074;3,4,5-Trichloro-1,2-diazine;Pyridazine,3,4,5-trichloro-
• CAS NO: 14161-11-6
• Molecular Formula: C₄HCl₃N₂
• Molecular Weight: 183.42
• EINECS: 238-006-2
• Mol File: 14161-11-6.mol
• Article Data: 16

Chemical Properties

• Melting Point: 56-58 °C
• Boiling Point: 322.8 °C at 760 mmHg
• Flash Point: 178.7 °C
• Appearance: /
• Density: 1.641 g/cm³
• Vapor Pressure: 0.000514mmHg at 25°C
• Refractive Index: 1.578
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• PKA: -2.14±0.10(Predicted)
• CAS DataBase Reference: 3,4,5-TRICHLOROPYRIDAZINE(CAS DataBase Reference)
• NIST Chemistry Reference: 3,4,5-TRICHLOROPYRIDAZINE(14161-11-6)
• EPA Substance Registry System: 3,4,5-TRICHLOROPYRIDAZINE(14161-11-6)

Safety Data

• Hazard Codes: Xi,Xn
• Statements: 22-36/38-43
• Safety Statements: 26
• RIDADR: 1759
• HazardClass: 8
• PackingGroup: III
• Hazardous Substances Data: 14161-11-6(Hazardous Substances Data)

Usage

General Description

3,4,5-Trichloropyridazine is a chemical compound that falls under the category of pyridazines, which are heterocyclic aromatic organic compounds. This specific compound is characterized by the presence of three chlorine atoms substituted at the 3rd, 4th, and 5th positions of its pyridazine ring. There is little available information regarding the specific properties or uses of 3,4,5-Trichloropyridazine. Its structure signifies potential bioactivity, which could potentially be utilized within various scientific or industrial applications, but further research is needed to fully understand its potential uses and effects.

InChI:InChI=1/C4HCl3N2/c5-2-1-8-9-4(7)3(2)6/h1H

Upstream product

• 932-22-9 4,5-Dichloro-3-hydroxypyridazine 
• 932-22-9 4,5-dichloro-2H-pyridazin-3-one 
• 186581-53-3 diazomethane 
• 6262-42-6 1,2,3,3-tetrachlorocyclopropene 

Downstream Products

• 27225-84-9 3-chloro-5-methyl-5H-benzo[b]pyridazino[4,3-e][1,4]oxazine 
• 2843-10-9 N-methyl-2-(10-methyl-10H-benzo[b]pyridazino[3,4-e][1,4]thiazin-4-ylsulfanyl)-aniline 
• 2843-08-5 2-(10H-benzo[b]pyridazino[3,4-e][1,4]thiazin-4-ylsulfanyl)-aniline 
• 64820-77-5 10-benzyl-1-chloro-10H-benzo[b]pyridazino[4,5-e][1,4]oxazine 
• 27225-87-2 5-benzyl-3-chloro-5H-benzo[b]pyridazino[4,3-e][1,4]oxazine 
• 89180-50-7 5-amino-3,4-dichloropyridazine 
• 53180-76-0 (3,5-dichloropyridazin-4-yl)amine 
• 2288-74-6 3,5-dichloro-4-methoxypyridazine 
• 1417632-80-4 2-[(5,6-dichloropyridazin-4-yl)methylamino]ethanol 
• 13645-43-7 4,5-dichloro-6-nitropyridazin-3(2H)-one 
• 20744-39-2 4-aminopyridazine 

Relevant articles and documents

4, 5-Substituted pyridazines. I.

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Substituted heteroaryl compounds and compositions and uses thereof (by machine translation)

The invention discloses substituted heteroaryl compounds and compositions thereof and their use. The compounds of formula (I) compound or type shown in (I) a compound represented by stereo isomers, tautomers, nitrogen oxide, solvate, metabolite, pharmaceutically acceptable salt or its prodrug. The invention also provides a pharmaceutical composition, the compounds and pharmaceutical compositions can be regulated protein kinase, particularly Aurora kinase and JAK kinase activity, for the prevention, treatment, treatment and reduce protein kinase, in particular JAK kinase activity mediated diseases or disorders. (by machine translation)

PROCESS FOR PREPARING 4-AMINO-PYRIDAZINES

The present invention relates to a process for preparing a pyridazine amine compound of formula V, and to processes for preparing dichloropyridazine amine compounds of formula IVa, IVb, or mixtures thereof. Furthermore, the present invention relates to the novel dichloropyridazine amine compounds of formula IVa, IVb,ormixtures thereof, wherein the amino group is an ethylamino group.