1416277-01-4

Basic information

• Product Name: (3-chlorophenyl)(mesityl)iodonium trifluoromethanesulfonate
• Synonyms: (3-chlorophenyl)(mesityl)iodonium trifluoromethanesulfonate
• CAS NO: 1416277-01-4
• Molecular Weight: 506.712
• Mol File: 1416277-01-4.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: (3-chlorophenyl)(mesityl)iodonium trifluoromethanesulfonate(CAS DataBase Reference)
• NIST Chemistry Reference: (3-chlorophenyl)(mesityl)iodonium trifluoromethanesulfonate(1416277-01-4)
• EPA Substance Registry System: (3-chlorophenyl)(mesityl)iodonium trifluoromethanesulfonate(1416277-01-4)

Safety Data

• Hazardous Substances Data: 1416277-01-4(Hazardous Substances Data)

Upstream product

• 625-99-0 3-iodochlorobenzene 
• 108-67-8 1,3,5-trimethyl-benzene 
• 1493-13-6 trifluorormethanesulfonic acid 

Downstream Products

• 108-37-2 1-bromo-3-chlorobenzene 
• 1618681-51-8 1-chloro-3-(3,3-dimethyl-2-phenylcyclopent-1-en-1-yl)benzene 
• 1618681-42-7 C₁₅H₁₅ClI⁽¹⁺⁾*F₆P^(1-) 
• 335259-42-2 3-(3-chlorophenyl)cyclohexan-1-one 
• 98-15-7 3-chlorotrifluoromethylbenzene 
• 7017-17-6 N-(3-chlorophenyl)isobutyramide 
• 1361004-95-6 7-chloro-3-methyl-2-(3-(4-(trifluoromethoxy)benzyl)phenyl)quinolin-4(1H)-one 
• 4028-63-1 iodomesitylene 
• 2050-67-1 PCB 11 
• 933674-85-2 1-chloro-3-(trifluoromethylsulfonyl)benzene 

Relevant articles and documents

Copper-mediated trifluoromethylation of diaryliodonium salts with difluoromethyltriflate

The reaction of diaryliodonium salts with difluoromethyltriflate in the presence of TBAT and CuTC gave the corresponding trifluoromethylated arenes in moderate yields. Compared to other difluorocarbene-derived trifluoromethylation reactions, the current one proceeded at mild reaction conditions (room temperature) within short reaction time (5 min).

N-Arylation of DABCO with Diaryliodonium Salts: General Synthesis of N-Aryl-DABCO Salts as Precursors for 1,4-Disubstituted Piperazines

Employing DABCO as a substrate, aryl(mesityl)iodonium triflates are introduced as arylating agents for a tertiary sp3-nitrogen. Mild conditions and exceptional selectivity of the aryl group transfer allow unprecedented N-aryl-DABCO salts to be obtained, bearing substituents of different electronic natures. This metal-free methodology has no analogy among known transition-metal-based reactions. The utility of isolated N-aryl-DABCO salts is demonstrated for the preparation of flibanserin.

Copper-mediated trifluoromethylation of diaryliodonium salts with TMSCF3 at room temperature

A convenient method for the preparation of trifluoromethylated arenes from the reaction of diaryliodonium salts with TMSCF3 in the presence of CuBF4·(MeCN)4 and KF at room temperature within 25 min was developed. This reaction provides a valuable complement to the previously established trifluoromethylation methods.