1416314-75-4

Basic information

• Product Name: N-benzyloxycarbonyl-3-fluoro-4-(4-(pyridin-2-yl)-1H-pyrazol-1-yl)aniline
• Synonyms: N-benzyloxycarbonyl-3-fluoro-4-(4-(pyridin-2-yl)-1H-pyrazol-1-yl)aniline
• CAS NO: 1416314-75-4
• Molecular Weight: 388.401
• Mol File: 1416314-75-4.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: N-benzyloxycarbonyl-3-fluoro-4-(4-(pyridin-2-yl)-1H-pyrazol-1-yl)aniline(CAS DataBase Reference)
• NIST Chemistry Reference: N-benzyloxycarbonyl-3-fluoro-4-(4-(pyridin-2-yl)-1H-pyrazol-1-yl)aniline(1416314-75-4)
• EPA Substance Registry System: N-benzyloxycarbonyl-3-fluoro-4-(4-(pyridin-2-yl)-1H-pyrazol-1-yl)aniline(1416314-75-4)

Safety Data

• Hazardous Substances Data: 1416314-75-4(Hazardous Substances Data)

Upstream product

• 493038-87-2 1H-3-amino-4-(pyridine-2-yl)-pyrazole 
• 2739-97-1 pyridine-2-acetonitrile 
• 127350-92-9 (2-fluoro-4-nitrophenyl)hydrazine 
• 369-34-6 3,4-difluoronitrobenzene 

Downstream Products

• 1416314-55-0 (S)-N-((3-(3-fluoro-4-(4-(pyridin-2-yl)-1H-pyrazol-1-yl)phenyl)-2-oxo-oxazolidin-5-yl)methyl)acetamide 

Relevant articles and documents

A oxazolidinone antibacterial compound of intermediate and its preparation method

The invention provides a new intermediate compound 2-(1-(2-fluoro-4-nitrophenyl)-1H-pyrazole-3(5)-amino-4-yl)pyridine represented by formula 4 in the production process of a compound (S)-N-{[3-(3-fluoro-4-(4-(2-pyridyl)pyrazolyl)phenyl)-2-oxazolidine-5-yl]methyl}acetamide, and a preparation method thereof. The new intermediate guarantees the abundant source of synthesis raw materials, reduces the cost of the raw materials, omits a complicated column chromatography purifying technology, makes the operation simple, and makes the amplified production of the target compound possible.

Oxazolidinone Compounds and Their Uses in Preparation of Antibiotics

The invention belongs to the field of medicaments, and particularly relates to oxazolidinone compounds and their uses in the preparation of antibiotics. A technical problem to be solved by the invention is to provide new oxazolidinone compounds having the structure represented by Formula I. The oxazolidinone compounds of the invention, which are new compounds obtained through numerous screening, have significant antibacterial activity against bacteria such as drug-resistant staphylococcus aureus, fecal coliform bacteria, and streptococcus pneumoniae, while exhibiting low toxicity. The invention provides new options for the development and application of antibiotics.